Human Reproduction vol.12 no.7 pp.1434–1435, 1997
Two successful pregnancies in a 46,XY patient A.K.S.Kan1,3 H.I.Abdalla1 and T.Oskarsson2 on both sides and an infantile uterus. Bilateral gonadectomy was carried out due to the risk of malignancy.1Fertility and Endocrinology Centre, In Vitro Fertilisation Unit, She was treated with oestrogen replace...
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| Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.586.7595 http://humrep.oxfordjournals.org/content/12/7/1434.full.pdf |
| Summary: | Two successful pregnancies in a 46,XY patient A.K.S.Kan1,3 H.I.Abdalla1 and T.Oskarsson2 on both sides and an infantile uterus. Bilateral gonadectomy was carried out due to the risk of malignancy.1Fertility and Endocrinology Centre, In Vitro Fertilisation Unit, She was treated with oestrogen replacement therapy andLister Hospital, London SW1W 8RH, UK and 2National University underwent normal pubertal physical changes and was onHospital, IVF unit, Reykjavik, Iceland hormonal replacement therapy right up to when she first3To whom correspondence should be addressed consulted our unit at the age of 30 years to be considered for Two successful pregnancies (singleton followed by twins) oocyte donation. Blood investigations done just prior to our first following ovum donation/in-vitro fertilization in a 46,XY consultations showed the following results: follicle stimulating woman have been studied. Although similar cases have hormone, 18.2 IU/l; luteinizing hormone, 6.6 IU/l; testosterone, previously been presented: in a pure XY patient and in a 0.6 nmol/l. Vaginal ultrasound showed a retroflexed uterus, 45,X/46,XY patient, this case is one in which a subsequent with a cervico-fundal height of 65 mm, anterio-posterior successful pregnancy has resulted. In such patients, the diameter of 25 mm and a transverse diameter of 35 mm. rate of Caesarean section appears to be increased, and we Endometrium was 8 mm thick on day 10 of her hormonal postulate that the hypoplastic nature of the uterus, although replacement therapy cycle and no abnormalities were seen able to respond quite well to both exogenous and endogen- in the adnexa. Semen analysis on husband’s spermatozoa |
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