CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study
Objective: To study whether serum parathyroid hormone (PTH) and serum calcium are associated with body mass index (BMI), and their predicting role in obesity. Design: Population based, cross-sectional study. Methods: In 2001 a population-based health survey was held in Tromsø, North Norway. Question...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.562.5692 2023-05-15T17:39:24+02:00 CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study Elena Kamycheva Johan Sundsfjord Rolf Jorde The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.562.5692 http://www.eje-online.org/content/151/2/167.full.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.562.5692 http://www.eje-online.org/content/151/2/167.full.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.eje-online.org/content/151/2/167.full.pdf text ftciteseerx 2016-01-08T12:06:42Z Objective: To study whether serum parathyroid hormone (PTH) and serum calcium are associated with body mass index (BMI), and their predicting role in obesity. Design: Population based, cross-sectional study. Methods: In 2001 a population-based health survey was held in Tromsø, North Norway. Question-naires on medical history and life-style factors were completed and anthropometric data were col-lected. Calcium and vitamin D intakes and a physical activity score were calculated. Serum calcium and PTH were measured in a subset of 3447 men and 4507 women. Pearson correlation and linear regression were used to evaluate associations between BMI, PTH and serum calcium, and logistic regression was used to test PTH and serum calcium as predictors of obesity and to calcu-late odds ratio. Relative risk was calculated using frequency tables. Results: For serum calcium and PTH there was a significant positive relation to BMI in both genders (P, 0.001), which to our knowledge has not previously been reported on the basis of a large epide-miological study. Age, low calcium and vitamin D intakes were explanatory variables for serum PTH. The highest quartile of serum PTH (.4.20 pmol/l) was a significant predictor for obesity (P, 0.001) in both genders, adjusted for age, physical activity and serum calcium. Obesity rates were higher in those with PTH levels in the highest quartile compared with those in the lower quartiles, which resulted in a relative risk of 1.40 (95 % confidence interval (C.I.) 1.20–1.60) for men and 1.48 (95 % C.I. 1.31–1.67) for women. Conclusions: Serum PTH, adjusted for age, physical activity and serum calcium, is positively associated with BMI in both sexes, and serum PTH is an independent predictor of obesity in our statistical model. European Journal of Endocrinology 151 167–172 Text North Norway Tromsø Unknown Norway Tromsø |
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ftciteseerx |
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English |
description |
Objective: To study whether serum parathyroid hormone (PTH) and serum calcium are associated with body mass index (BMI), and their predicting role in obesity. Design: Population based, cross-sectional study. Methods: In 2001 a population-based health survey was held in Tromsø, North Norway. Question-naires on medical history and life-style factors were completed and anthropometric data were col-lected. Calcium and vitamin D intakes and a physical activity score were calculated. Serum calcium and PTH were measured in a subset of 3447 men and 4507 women. Pearson correlation and linear regression were used to evaluate associations between BMI, PTH and serum calcium, and logistic regression was used to test PTH and serum calcium as predictors of obesity and to calcu-late odds ratio. Relative risk was calculated using frequency tables. Results: For serum calcium and PTH there was a significant positive relation to BMI in both genders (P, 0.001), which to our knowledge has not previously been reported on the basis of a large epide-miological study. Age, low calcium and vitamin D intakes were explanatory variables for serum PTH. The highest quartile of serum PTH (.4.20 pmol/l) was a significant predictor for obesity (P, 0.001) in both genders, adjusted for age, physical activity and serum calcium. Obesity rates were higher in those with PTH levels in the highest quartile compared with those in the lower quartiles, which resulted in a relative risk of 1.40 (95 % confidence interval (C.I.) 1.20–1.60) for men and 1.48 (95 % C.I. 1.31–1.67) for women. Conclusions: Serum PTH, adjusted for age, physical activity and serum calcium, is positively associated with BMI in both sexes, and serum PTH is an independent predictor of obesity in our statistical model. European Journal of Endocrinology 151 167–172 |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Elena Kamycheva Johan Sundsfjord Rolf Jorde |
spellingShingle |
Elena Kamycheva Johan Sundsfjord Rolf Jorde CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
author_facet |
Elena Kamycheva Johan Sundsfjord Rolf Jorde |
author_sort |
Elena Kamycheva |
title |
CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
title_short |
CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
title_full |
CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
title_fullStr |
CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
title_full_unstemmed |
CLINICAL STUDY Serum parathyroid hormone level is associated with body mass index. The 5th Tromsø study |
title_sort |
clinical study serum parathyroid hormone level is associated with body mass index. the 5th tromsø study |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.562.5692 http://www.eje-online.org/content/151/2/167.full.pdf |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
North Norway Tromsø |
genre_facet |
North Norway Tromsø |
op_source |
http://www.eje-online.org/content/151/2/167.full.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.562.5692 http://www.eje-online.org/content/151/2/167.full.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766140161985347584 |