c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors
Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus,...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Text |
Language: | English |
Subjects: | |
Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.559.6208 http://www.ias.ac.in/jgenet/Vol88No1/41.pdf |
id |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.559.6208 |
---|---|
record_format |
openpolar |
spelling |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.559.6208 2023-05-15T15:50:16+02:00 c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors Muhammad Moaeen-ud-din Li Guo Yang The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.559.6208 http://www.ias.ac.in/jgenet/Vol88No1/41.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.559.6208 http://www.ias.ac.in/jgenet/Vol88No1/41.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.ias.ac.in/jgenet/Vol88No1/41.pdf text ftciteseerx 2016-01-08T11:56:32Z Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis domestica, Homo sapi-ens, Sus scrofa, Bos taurus, Mus musculus, Rattus norvegicus, Canis lupus familiaris, Ovis aries, Equus caballus, Pan troglodytes and Macaca mulatto to identify somatostatin and somatostatin receptors in each species. To date, we have identi-fied a minimum of two genes of somatostatin and five somatostatin receptor genes in mammalian species with variable forms. We established a clear evolutionary history of the somatostatin system and traced the origin of the somatostatin system to 395 million years ago (MYA), identifying critical steps in their evolution. [Moaeen-ud-Din M. and Yang L. G. 2009 Evolutionary history of the somatostatin and somatostatin receptors. J. Genet. 88, 41–53] Text Canis lupus Unknown Indian |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftciteseerx |
language |
English |
description |
Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis domestica, Homo sapi-ens, Sus scrofa, Bos taurus, Mus musculus, Rattus norvegicus, Canis lupus familiaris, Ovis aries, Equus caballus, Pan troglodytes and Macaca mulatto to identify somatostatin and somatostatin receptors in each species. To date, we have identi-fied a minimum of two genes of somatostatin and five somatostatin receptor genes in mammalian species with variable forms. We established a clear evolutionary history of the somatostatin system and traced the origin of the somatostatin system to 395 million years ago (MYA), identifying critical steps in their evolution. [Moaeen-ud-Din M. and Yang L. G. 2009 Evolutionary history of the somatostatin and somatostatin receptors. J. Genet. 88, 41–53] |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Muhammad Moaeen-ud-din Li Guo Yang |
spellingShingle |
Muhammad Moaeen-ud-din Li Guo Yang c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
author_facet |
Muhammad Moaeen-ud-din Li Guo Yang |
author_sort |
Muhammad Moaeen-ud-din |
title |
c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
title_short |
c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
title_full |
c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
title_fullStr |
c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
title_full_unstemmed |
c © Indian Academy of Sciences RESEARCH ARTICLE Evolutionary history of the somatostatin and somatostatin receptors |
title_sort |
c © indian academy of sciences research article evolutionary history of the somatostatin and somatostatin receptors |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.559.6208 http://www.ias.ac.in/jgenet/Vol88No1/41.pdf |
geographic |
Indian |
geographic_facet |
Indian |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_source |
http://www.ias.ac.in/jgenet/Vol88No1/41.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.559.6208 http://www.ias.ac.in/jgenet/Vol88No1/41.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766385243534655488 |