Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients
The low incidence of coronary heart disease in Greenland Eskimos and Japanese fishermen who have high consumption of fish and seafood has called the attention in the role of eicosapentaenoic (EPA = 20:5n-3) and docosahexaenoic (DHA = 22:6n-3) acids, the major n-3 polyunsaturated fatty acids (PUFAs)...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.557.5983 2023-05-15T16:07:17+02:00 Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients Supanee Putadechakum Vichai Tanphaichitr Preeya Leelahagul Varapat Pakpeankitvatana The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.557.5983 http://www.mat.or.th/journal/files/Vol88_No2_181.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.557.5983 http://www.mat.or.th/journal/files/Vol88_No2_181.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.mat.or.th/journal/files/Vol88_No2_181.pdf text ftciteseerx 2016-01-08T11:51:06Z The low incidence of coronary heart disease in Greenland Eskimos and Japanese fishermen who have high consumption of fish and seafood has called the attention in the role of eicosapentaenoic (EPA = 20:5n-3) and docosahexaenoic (DHA = 22:6n-3) acids, the major n-3 polyunsaturated fatty acids (PUFAs) in fish oils, in reducing cardiovascular risk. N-3 PUFAs may reduce serum lipids by promoting fatty acid oxidation and decrease VLDL producing from the liver, depress tissue arachidonate synthesis and alter the composition and tissue PUFAs. Plasma lipoprotein and fatty acid composition of total serum and erythrocyte lipids in 9 hypertriglyceridemic patients consisting of 4 males and 5 females aged 39-72 yr who attended the Nutrition Clinic, Ramathibodi Hospital were investigated. The study period consisted of 4 wks of dietary advice only followed by 48 wks of dietary advice with a daily intake of 6 g of fish oil capsules (FOC). Six grams of FOC provided 1080 mg of 20:5n-3 and 720 mg of 22:6n-3.Their plasma triglyceride (TG) levels at wk 0, 12, 24, 36, 48 were 356.7, 230.1, 209.7, 192.9, 227.4 mg/dL and M-particle (equivalent to very low density lipoprotein, VLDL) were 484.4, 354.8, 383.1, 349.7, 453.2 mg/dL respectively that decreased significantly, whereas their plasma low density lipoprotein cholesterol (LDL-C) levels at the same periods were 139.4, 164.9, 171.0, 157.1, 158.3 mg/dL that increased significantly. Serum and erythrocyte 20:5n-3 and 22:6n-3 in these sub- Text eskimo* Greenland Unknown Greenland |
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Open Polar |
collection |
Unknown |
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ftciteseerx |
language |
English |
description |
The low incidence of coronary heart disease in Greenland Eskimos and Japanese fishermen who have high consumption of fish and seafood has called the attention in the role of eicosapentaenoic (EPA = 20:5n-3) and docosahexaenoic (DHA = 22:6n-3) acids, the major n-3 polyunsaturated fatty acids (PUFAs) in fish oils, in reducing cardiovascular risk. N-3 PUFAs may reduce serum lipids by promoting fatty acid oxidation and decrease VLDL producing from the liver, depress tissue arachidonate synthesis and alter the composition and tissue PUFAs. Plasma lipoprotein and fatty acid composition of total serum and erythrocyte lipids in 9 hypertriglyceridemic patients consisting of 4 males and 5 females aged 39-72 yr who attended the Nutrition Clinic, Ramathibodi Hospital were investigated. The study period consisted of 4 wks of dietary advice only followed by 48 wks of dietary advice with a daily intake of 6 g of fish oil capsules (FOC). Six grams of FOC provided 1080 mg of 20:5n-3 and 720 mg of 22:6n-3.Their plasma triglyceride (TG) levels at wk 0, 12, 24, 36, 48 were 356.7, 230.1, 209.7, 192.9, 227.4 mg/dL and M-particle (equivalent to very low density lipoprotein, VLDL) were 484.4, 354.8, 383.1, 349.7, 453.2 mg/dL respectively that decreased significantly, whereas their plasma low density lipoprotein cholesterol (LDL-C) levels at the same periods were 139.4, 164.9, 171.0, 157.1, 158.3 mg/dL that increased significantly. Serum and erythrocyte 20:5n-3 and 22:6n-3 in these sub- |
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The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Supanee Putadechakum Vichai Tanphaichitr Preeya Leelahagul Varapat Pakpeankitvatana |
spellingShingle |
Supanee Putadechakum Vichai Tanphaichitr Preeya Leelahagul Varapat Pakpeankitvatana Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
author_facet |
Supanee Putadechakum Vichai Tanphaichitr Preeya Leelahagul Varapat Pakpeankitvatana |
author_sort |
Supanee Putadechakum |
title |
Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
title_short |
Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
title_full |
Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
title_fullStr |
Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
title_full_unstemmed |
Levels and Fatty Acid Composition of Total Serum and Erythrocyte Lipids in Hypertriglyceridemic Patients |
title_sort |
levels and fatty acid composition of total serum and erythrocyte lipids in hypertriglyceridemic patients |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.557.5983 http://www.mat.or.th/journal/files/Vol88_No2_181.pdf |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
eskimo* Greenland |
genre_facet |
eskimo* Greenland |
op_source |
http://www.mat.or.th/journal/files/Vol88_No2_181.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.557.5983 http://www.mat.or.th/journal/files/Vol88_No2_181.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766403348739653632 |