Effect of Tobacco as Fumigant on Lungs and Intestine of Rattus rattus

• Main Authors: Rashmi Joshi, K. S. Rana, Agra College
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Subjects: Key words; Nicotiana tobacum; Rattus rattus; Hyperplasia; Emphysema; Intestinal mucosa
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.527.8792; http://www.ajes.in/pdfs/09-1/28. effect of tobacco (pdf).pdf

Abstract: After treatment of tobacco fumes for 1, 3 and 6 months the histological examination of the vital parts of Rattus rattus i.e. body-lungs, stomach and intestine, reveals few changes such as the loss of lung tissues with signs of emphysema, bronchoconstriction in the lungs. The body weight increases and the lung weight were significantly suppressed. The lungs showed wall thickness were decreased. The stomach showed ulcer margin hyperemia and some animals showed apoptic cells in the mucus layer. Intestinal mucosa showed drastically stimulated and was devoid of villi. In large intestine no significant change was observed.