Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia
We have characterized the elevation of circulating catecholamines in the intact Atlantic cod (Gadus morhua) during graded acute (30 min) hypoxia. The potential mechanisms contributing to the mobilization of catecholamines during hypoxia were then assessed in vivo using nerve sectioning and pharmacol...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.526.2094 2023-05-15T15:27:08+02:00 Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia F. Perry Regina Fritsche Richard Kinkead Stefan Nilsson The Pennsylvania State University CiteSeerX Archives 1991 application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.2094 http://jeb.biologists.org/content/155/1/549.full.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.2094 http://jeb.biologists.org/content/155/1/549.full.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://jeb.biologists.org/content/155/1/549.full.pdf text 1991 ftciteseerx 2016-01-08T10:22:04Z We have characterized the elevation of circulating catecholamines in the intact Atlantic cod (Gadus morhua) during graded acute (30 min) hypoxia. The potential mechanisms contributing to the mobilization of catecholamines during hypoxia were then assessed in vivo using nerve sectioning and pharmacological techniques and in situ using a perfused head kidney preparation. Pre-branchial plasma adrenaline concentrations were significantly elevated at all levels of aquatic hypoxia utilised [water Po, (/VO2) = 10kPa (75mmHg), 7.3kPa (55mmHg) or 5.3 kPa (40mmHg)], whereas noradrenaline levels did not increase significantly in these particular experiments in which PwO2 was lowered gradually over a 30 min period. All subsequent experiments were performed using a more rapid induction of hypoxia to reach a final AvO2 of 5.3 kPa within the first 5-10 min of exposure. Blood withdrawn from pre-branchial (ventral aortic) and post-branchial (dorsal aortic) cannulae after 30 min revealed pronounced re-ductions in PO2 and O2 content (COz) as well as elevated pH. These data support the notion that blood acidosis is not a prerequisite for catecholamine mobilization Text atlantic cod Gadus morhua Unknown |
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English |
description |
We have characterized the elevation of circulating catecholamines in the intact Atlantic cod (Gadus morhua) during graded acute (30 min) hypoxia. The potential mechanisms contributing to the mobilization of catecholamines during hypoxia were then assessed in vivo using nerve sectioning and pharmacological techniques and in situ using a perfused head kidney preparation. Pre-branchial plasma adrenaline concentrations were significantly elevated at all levels of aquatic hypoxia utilised [water Po, (/VO2) = 10kPa (75mmHg), 7.3kPa (55mmHg) or 5.3 kPa (40mmHg)], whereas noradrenaline levels did not increase significantly in these particular experiments in which PwO2 was lowered gradually over a 30 min period. All subsequent experiments were performed using a more rapid induction of hypoxia to reach a final AvO2 of 5.3 kPa within the first 5-10 min of exposure. Blood withdrawn from pre-branchial (ventral aortic) and post-branchial (dorsal aortic) cannulae after 30 min revealed pronounced re-ductions in PO2 and O2 content (COz) as well as elevated pH. These data support the notion that blood acidosis is not a prerequisite for catecholamine mobilization |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
F. Perry Regina Fritsche Richard Kinkead Stefan Nilsson |
spellingShingle |
F. Perry Regina Fritsche Richard Kinkead Stefan Nilsson Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
author_facet |
F. Perry Regina Fritsche Richard Kinkead Stefan Nilsson |
author_sort |
F. Perry |
title |
Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
title_short |
Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
title_full |
Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
title_fullStr |
Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
title_full_unstemmed |
Control of catecholamine release in vivo and in situ in the Atlantic cod (Gadus morhua) during hypoxia |
title_sort |
control of catecholamine release in vivo and in situ in the atlantic cod (gadus morhua) during hypoxia |
publishDate |
1991 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.2094 http://jeb.biologists.org/content/155/1/549.full.pdf |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_source |
http://jeb.biologists.org/content/155/1/549.full.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.2094 http://jeb.biologists.org/content/155/1/549.full.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766357592372674560 |