AND MARJO-RIITTA JÄRVELINb,g
ABSTRACT: Allergen-induced secretion of Th2-type cytokines and IgE produc-tion have recently been reported to be increased in mice treated with 1,25(OH)2D, the active form of vitamin D. Our objective was to investigate whether vitamin D supplementation in infancy is associated with the risk of atopy...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.519.5420 2023-05-15T17:42:17+02:00 AND MARJO-RIITTA JÄRVELINb,g Infant Vitamin Acentre For Paediatric Epidemiology The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.519.5420 http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.519.5420 http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf text ftciteseerx 2016-01-08T10:01:13Z ABSTRACT: Allergen-induced secretion of Th2-type cytokines and IgE produc-tion have recently been reported to be increased in mice treated with 1,25(OH)2D, the active form of vitamin D. Our objective was to investigate whether vitamin D supplementation in infancy is associated with the risk of atopy, allergic rhinitis, and asthma. The Northern Finland Birth Cohort con-sists of all individuals in the two most northern provinces of Finland who were due to be born in 1966. Data on vitamin D supplementation during the first year of life was obtained in 1967. Current asthma and allergic rhinitis were re-ported at age 31 years (n = 7,648), and atopy determined by skin-prick test in a sub-sample still living in northern Finland or the Helsinki area (n = 5,007). The prevalence of atopy and allergic rhinitis at age 31 years was higher in par-ticipants who had received vitamin D supplementation regularly during the first year compared to others (OR 1.46, 95%CI 1.4–2.0, and OR 1.66, 95%CI 1.1–1.6, respectively). A similar association was observed for asthma (OR 1.35, 95%CI 0.99–1.8). These associations persisted after adjustment for a wide Text Northern Finland Unknown |
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Open Polar |
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Unknown |
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ftciteseerx |
language |
English |
description |
ABSTRACT: Allergen-induced secretion of Th2-type cytokines and IgE produc-tion have recently been reported to be increased in mice treated with 1,25(OH)2D, the active form of vitamin D. Our objective was to investigate whether vitamin D supplementation in infancy is associated with the risk of atopy, allergic rhinitis, and asthma. The Northern Finland Birth Cohort con-sists of all individuals in the two most northern provinces of Finland who were due to be born in 1966. Data on vitamin D supplementation during the first year of life was obtained in 1967. Current asthma and allergic rhinitis were re-ported at age 31 years (n = 7,648), and atopy determined by skin-prick test in a sub-sample still living in northern Finland or the Helsinki area (n = 5,007). The prevalence of atopy and allergic rhinitis at age 31 years was higher in par-ticipants who had received vitamin D supplementation regularly during the first year compared to others (OR 1.46, 95%CI 1.4–2.0, and OR 1.66, 95%CI 1.1–1.6, respectively). A similar association was observed for asthma (OR 1.35, 95%CI 0.99–1.8). These associations persisted after adjustment for a wide |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Infant Vitamin Acentre For Paediatric Epidemiology |
spellingShingle |
Infant Vitamin Acentre For Paediatric Epidemiology AND MARJO-RIITTA JÄRVELINb,g |
author_facet |
Infant Vitamin Acentre For Paediatric Epidemiology |
author_sort |
Infant Vitamin |
title |
AND MARJO-RIITTA JÄRVELINb,g |
title_short |
AND MARJO-RIITTA JÄRVELINb,g |
title_full |
AND MARJO-RIITTA JÄRVELINb,g |
title_fullStr |
AND MARJO-RIITTA JÄRVELINb,g |
title_full_unstemmed |
AND MARJO-RIITTA JÄRVELINb,g |
title_sort |
and marjo-riitta järvelinb,g |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.519.5420 http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.519.5420 http://www.direct-ms.org/pdf/VitDNonAuto/Hypponen Vit D allergy 06.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766144120200364032 |