Onto Hybrid Organic-inorganic Mesoporous Materials

• Main Authors: Candida Lipase, B Immobilization, Brindusa Dragoi, Emil Dumitriu
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Subjects: MCM-41; functionalization; immobilization; Candida antarctica lipase B; alcoholysis; Antarc*; Antarctica
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.508.790; http://acta.chem-soc.si/55/55-2-277.pdf

Based on MCM-41 mesoporous silica, three different hybrid organic-inorganic mesoporous materials were synthesized. Functionalization and hydrophobization of MCM-41 with 3-aminopropyltriethoxysilane (APTES), chlorotrimethylsila-ne (CTMS), and propyltrimethoxysilane (PTMS) were carried out by post-synthesis method after the removal of hexa-decyltrimethylammonium bromide used as template. The effect of grafted organosilanes on the mesostructural proper-ties of the resulted hybrid materials was systematically analyzed by different techniques such as X-ray diffraction (XRD), N2 adsorption isotherms, FT-IR and 29Si MAS NMR. Functionalized MCM-41 samples were used as support for Candida antarctica lipase B (CALB) immobilization. The activity of the new biocatalysts was evaluated in the alco-holysis of ethyl acetate with two alcohols (1-hexanol and 1-butanol, respectively) and compared with that of the free enzyme. All reactions were performed in organic media using n-hexane as solvent.