Effects of growth hormone and insulin-like growth factor I on salinity tolerance and q q gill Na ,K -ATPase in Atlantic salmon Ž Salmo salar .: interaction with cortisol. Gen

• Main Author: Stephen D. Mccormick
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Published: 1996
• Subjects: Atlantic salmon; Salmo salar
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.419.914; http://www.bio.umass.edu/biology/mccormick/pdf/gce 96 GH IGF sal tol.pdf

The potential roles of growth hormone (GH) and insulin-like growth factor I (IGF-I) in seawater (SW) acclimation of juvenile Atlantic salmon (Salmo salar) were examined. Compared to controls, fish in 12 ppt seawater given one or three injections (2–6 days) of GH (ovine, 0.2 µg ·g −1) or IGF-I (recombinant bovine, 0.05–0.2 µg ·g −1) had significantly greater salinity tolerance as judged by lower plasma sodium, osmolality, and muscle moisture content following transfer to 34 ppt. Single injections of GH and IGF-I in fish in fresh water failed to improve salinity tolerance following transfer to 25 ppt SW. Treatment of fish in 12 ppt with GH or IGF-I for 2–6 days did not increase gill Na +,K +-ATPase activity, but treatment with GH prevented decreases in gill Na +, K +-ATPase activity that occurred in controls following