Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice
Japanese house mice (Mus musculus molossinus) are thought to be a hybrid lineage derived from two prehistoric immigrants, the subspecies M. m. musculus of northern Eurasia and M. m. castaneus of South Asia. Mice of the western European subspecies M. m. domesticus have been detected in Japanese ports...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.363.5786 2023-05-15T18:09:10+02:00 Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice Mitsuo Nunome Chikako Ishimori Ken P. Aplin Kimiyuki Tsuchiya Hiromichi Yonekawa Kazuo Moriwaki Hitoshi Suzuki The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.363.5786 http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.363.5786 http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf intron sequences Japanese wild mice Mus musculus phylogeography recombination text ftciteseerx 2016-01-08T00:56:38Z Japanese house mice (Mus musculus molossinus) are thought to be a hybrid lineage derived from two prehistoric immigrants, the subspecies M. m. musculus of northern Eurasia and M. m. castaneus of South Asia. Mice of the western European subspecies M. m. domesticus have been detected in Japanese ports and airports only. We examined haplotype structuring of a 200 kb stretch on chromosome 8 for 59 mice from throughout Eurasia, determining short segments ( 370–600 bp) of eight nuclear genes (Fanca, Spire2, Tcf25, Mc1r, Tubb3, Def8, Afg3l1 and Dbndd1) which are intermittently arranged in this order. Where possible we identified the subspecies origin for individual gene alleles and then designated haplotypes for concatenated alleles. We recovered 11 haplotypes among 19 Japanese mice examined, identified either as ‘intact ’ haplotypes derived from the subspecies musculus (57.9%), domesticus (7.9%), and castaneus (2.6%), or as ‘recombinant’ haplotypes (31.6%). We also detected recombinant haplotypes unique to Sakhalin. The complex nature of the recombinant haplotypes suggests ancient introduction of all three subspecies components into the peripheral part of Eurasia or complicated genomic Text Sakhalin Unknown |
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English |
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intron sequences Japanese wild mice Mus musculus phylogeography recombination |
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intron sequences Japanese wild mice Mus musculus phylogeography recombination Mitsuo Nunome Chikako Ishimori Ken P. Aplin Kimiyuki Tsuchiya Hiromichi Yonekawa Kazuo Moriwaki Hitoshi Suzuki Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
topic_facet |
intron sequences Japanese wild mice Mus musculus phylogeography recombination |
description |
Japanese house mice (Mus musculus molossinus) are thought to be a hybrid lineage derived from two prehistoric immigrants, the subspecies M. m. musculus of northern Eurasia and M. m. castaneus of South Asia. Mice of the western European subspecies M. m. domesticus have been detected in Japanese ports and airports only. We examined haplotype structuring of a 200 kb stretch on chromosome 8 for 59 mice from throughout Eurasia, determining short segments ( 370–600 bp) of eight nuclear genes (Fanca, Spire2, Tcf25, Mc1r, Tubb3, Def8, Afg3l1 and Dbndd1) which are intermittently arranged in this order. Where possible we identified the subspecies origin for individual gene alleles and then designated haplotypes for concatenated alleles. We recovered 11 haplotypes among 19 Japanese mice examined, identified either as ‘intact ’ haplotypes derived from the subspecies musculus (57.9%), domesticus (7.9%), and castaneus (2.6%), or as ‘recombinant’ haplotypes (31.6%). We also detected recombinant haplotypes unique to Sakhalin. The complex nature of the recombinant haplotypes suggests ancient introduction of all three subspecies components into the peripheral part of Eurasia or complicated genomic |
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The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Mitsuo Nunome Chikako Ishimori Ken P. Aplin Kimiyuki Tsuchiya Hiromichi Yonekawa Kazuo Moriwaki Hitoshi Suzuki |
author_facet |
Mitsuo Nunome Chikako Ishimori Ken P. Aplin Kimiyuki Tsuchiya Hiromichi Yonekawa Kazuo Moriwaki Hitoshi Suzuki |
author_sort |
Mitsuo Nunome |
title |
Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
title_short |
Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
title_full |
Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
title_fullStr |
Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
title_full_unstemmed |
Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice |
title_sort |
detection of recombinant haplotypes in wild mice (mus musculus) provides new insights into the origin of japanese mice |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.363.5786 http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf |
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Sakhalin |
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Sakhalin |
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http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.363.5786 http://www.eebweb.arizona.edu/nachman/Suggested Papers/Prior papers/Nunome_2010.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766181626102939648 |