Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi
Abstract: Hypertension or high blood pressure is one of the major independent risk factors for cardiovascular diseases. Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in regulation of blood pressure by converting angiotensin I to angiotensin II, a potent vas...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.354.4342 2023-05-15T13:09:23+02:00 Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi Isuru Wijesekara Se-kwon Kim The Pennsylvania State University CiteSeerX Archives application/zip http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4342 en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4342 Metadata may be used without restrictions as long as the oai identifier remains attached to it. ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/9e/63/Mar_Drugs_2010_Mar_31_8(4)_1080-1093.tar.gz Abbreviations ACE angiotensin-I-converting enzyme COS chitooligosaccharides text ftciteseerx 2016-01-08T00:30:03Z Abstract: Hypertension or high blood pressure is one of the major independent risk factors for cardiovascular diseases. Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in regulation of blood pressure by converting angiotensin I to angiotensin II, a potent vasoconstrictor. Therefore, the inhibition of ACE activity is a major target in the prevention of hypertension. Recently, the search for natural ACE inhibitors as alternatives to synthetic drugs is of great interest to prevent several side effects and a number of novel compounds such as bioactive peptides, chitooligosaccharide derivatives (COS) and phlorotannins have been derived from marine organisms as potential ACE inhibitors. These inhibitory derivatives can be developed as nutraceuticals and pharmaceuticals with potential to prevent hypertension. Hence, the aim of this review is to discuss the marine-derived ACE inhibitors and their future prospects as novel therapeutic drug candidates for treat hypertension. Text alaska pollock Alaska Unknown |
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English |
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Abbreviations ACE angiotensin-I-converting enzyme COS chitooligosaccharides |
spellingShingle |
Abbreviations ACE angiotensin-I-converting enzyme COS chitooligosaccharides Isuru Wijesekara Se-kwon Kim Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
topic_facet |
Abbreviations ACE angiotensin-I-converting enzyme COS chitooligosaccharides |
description |
Abstract: Hypertension or high blood pressure is one of the major independent risk factors for cardiovascular diseases. Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in regulation of blood pressure by converting angiotensin I to angiotensin II, a potent vasoconstrictor. Therefore, the inhibition of ACE activity is a major target in the prevention of hypertension. Recently, the search for natural ACE inhibitors as alternatives to synthetic drugs is of great interest to prevent several side effects and a number of novel compounds such as bioactive peptides, chitooligosaccharide derivatives (COS) and phlorotannins have been derived from marine organisms as potential ACE inhibitors. These inhibitory derivatives can be developed as nutraceuticals and pharmaceuticals with potential to prevent hypertension. Hence, the aim of this review is to discuss the marine-derived ACE inhibitors and their future prospects as novel therapeutic drug candidates for treat hypertension. |
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The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Isuru Wijesekara Se-kwon Kim |
author_facet |
Isuru Wijesekara Se-kwon Kim |
author_sort |
Isuru Wijesekara |
title |
Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
title_short |
Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
title_full |
Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
title_fullStr |
Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
title_full_unstemmed |
Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska Pollock surimi |
title_sort |
fractionation and angiotensin i-converting enzyme (ace) inhibitory activity of gelatin hydrolysates from by-products of alaska pollock surimi |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4342 |
genre |
alaska pollock Alaska |
genre_facet |
alaska pollock Alaska |
op_source |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/9e/63/Mar_Drugs_2010_Mar_31_8(4)_1080-1093.tar.gz |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4342 |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766174933784723456 |