Printed in U.S.A. Copyright © 1998 by The Endocrine Society Distribution, Characterization, and Growth Hormone- Releasing Activity of Pituitary Adenylate Cyclase- Activating Polypeptide in the European Eel, Anguilla anguilla*
PITUITARY adenylate cyclase-activating polypeptide (PACAP) was first isolated from the ovine hypothalamus on the basis of its ability to stimulate adenylyl cyclase activity in rat pituitary cells (1). The peptide was found to exist in two amidated forms with 38 (PACAP38) and 27 (PACAP27) amino acid...
Main Authors: | , , , , , , |
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Format: | Text |
Language: | English |
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Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.322.5713 http://endo.endojournals.org/content/139/10/4300.full.pdf |
Summary: | PITUITARY adenylate cyclase-activating polypeptide (PACAP) was first isolated from the ovine hypothalamus on the basis of its ability to stimulate adenylyl cyclase activity in rat pituitary cells (1). The peptide was found to exist in two amidated forms with 38 (PACAP38) and 27 (PACAP27) amino acid residues (2). The N-terminal portion of PACAP shows 68 % identity with vasoactive intestinal polypeptide (VIP), identifying PACAP as a member of the |
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