Open Access
No influence of oxygen levels on pathogenesis and virus shedding in Salmonid alphavirus (SAV)challenged Atlantic salmon (Salmo salar L.) Linda Andersen 1 * , Kjartan Hodneland 2, Are Nylund 1 Background: For more than three decades, diseases caused by salmonid alphaviruses (SAV) have become a major...
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Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.3644 http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf |
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.318.3644 2023-05-15T15:32:20+02:00 Open Access The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.3644 http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.3644 http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf text ftciteseerx 2016-09-04T00:11:53Z No influence of oxygen levels on pathogenesis and virus shedding in Salmonid alphavirus (SAV)challenged Atlantic salmon (Salmo salar L.) Linda Andersen 1 * , Kjartan Hodneland 2, Are Nylund 1 Background: For more than three decades, diseases caused by salmonid alphaviruses (SAV) have become a major problem of increasing economic importance in the European fish-farming industry. However, experimental infection trials with SAV result in low or no mortality i.e very different from most field outbreaks of pancreas disease (PD). This probably reflects the difficulties in reproducing complex biotic and abiotic field conditions in the laboratory. In this study we looked at the relationship between SAV-infection in salmon and sub-lethal environmental hypoxia as a result of reduced flow-through in tank systems. Results: The experiment demonstrated that constant reduced oxygen levels (60-65 % oxygen saturation: 6.5-7.0 mg/L) did not significantly increase the severity or the progress of pancreas disease (PD). These conclusions are based upon assessments of a semi-quantitative histopathological lesion score system, morbidities/mortalities, and levels of SAV RNA in tissues and water (measured by 1 MDS electropositive virus filters and downstream real-time Text Atlantic salmon Salmo salar Unknown Nylund ENVELOPE(6.855,6.855,62.805,62.805) Sav’ ENVELOPE(156.400,156.400,68.817,68.817) |
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Unknown |
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ftciteseerx |
language |
English |
description |
No influence of oxygen levels on pathogenesis and virus shedding in Salmonid alphavirus (SAV)challenged Atlantic salmon (Salmo salar L.) Linda Andersen 1 * , Kjartan Hodneland 2, Are Nylund 1 Background: For more than three decades, diseases caused by salmonid alphaviruses (SAV) have become a major problem of increasing economic importance in the European fish-farming industry. However, experimental infection trials with SAV result in low or no mortality i.e very different from most field outbreaks of pancreas disease (PD). This probably reflects the difficulties in reproducing complex biotic and abiotic field conditions in the laboratory. In this study we looked at the relationship between SAV-infection in salmon and sub-lethal environmental hypoxia as a result of reduced flow-through in tank systems. Results: The experiment demonstrated that constant reduced oxygen levels (60-65 % oxygen saturation: 6.5-7.0 mg/L) did not significantly increase the severity or the progress of pancreas disease (PD). These conclusions are based upon assessments of a semi-quantitative histopathological lesion score system, morbidities/mortalities, and levels of SAV RNA in tissues and water (measured by 1 MDS electropositive virus filters and downstream real-time |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
title |
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Open Access |
title_full |
Open Access |
title_fullStr |
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title_full_unstemmed |
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open access |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.3644 http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf |
long_lat |
ENVELOPE(6.855,6.855,62.805,62.805) ENVELOPE(156.400,156.400,68.817,68.817) |
geographic |
Nylund Sav’ |
geographic_facet |
Nylund Sav’ |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.3644 http://www.biomedcentral.com/content/pdf/1743-422X-7-198.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766362846777573376 |