HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus
Members of the HSP70 gene family comprising the constitutive (HSC70) and inducible (HSP70) genes, plus GRP78 (Glucose-regulated protein 78kDa) were surveyed for expression levels via Q-PCR after both an acute two-hour heat shock experiment and a time course assay in the Antarctic plunderfish Harpagi...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.318.2443 2023-05-15T14:00:08+02:00 HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus Melody S. Clark Keiron P. P. Fraser Gavin Burns Lloyd S. Peck The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.2443 http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.2443 http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf Antarctic Climate change stenothermal heat shock protein marine HSP_Harpagifer 3 text ftciteseerx 2016-09-04T00:11:39Z Members of the HSP70 gene family comprising the constitutive (HSC70) and inducible (HSP70) genes, plus GRP78 (Glucose-regulated protein 78kDa) were surveyed for expression levels via Q-PCR after both an acute two-hour heat shock experiment and a time course assay in the Antarctic plunderfish Harpagifer antarcticus. In general, down regulation of all genes was observed during the course of the heat shock experiments. This thermally induced down regulation was particularly acute for the GRP78 gene, which at one time point was more than 100 fold down regulated. These results demonstrate the loss of the heat shock response in H. antarcticus, a basal member of the Notothenioidei. This finding is discussed with reference to the survival of Notothenioids during observed ocean warming and also the reorganisation of cellular protein mechanisms of species living in extreme environments. Text Antarc* Antarctic antarcticus Unknown Antarctic The Antarctic |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftciteseerx |
language |
English |
topic |
Antarctic Climate change stenothermal heat shock protein marine HSP_Harpagifer 3 |
spellingShingle |
Antarctic Climate change stenothermal heat shock protein marine HSP_Harpagifer 3 Melody S. Clark Keiron P. P. Fraser Gavin Burns Lloyd S. Peck HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
topic_facet |
Antarctic Climate change stenothermal heat shock protein marine HSP_Harpagifer 3 |
description |
Members of the HSP70 gene family comprising the constitutive (HSC70) and inducible (HSP70) genes, plus GRP78 (Glucose-regulated protein 78kDa) were surveyed for expression levels via Q-PCR after both an acute two-hour heat shock experiment and a time course assay in the Antarctic plunderfish Harpagifer antarcticus. In general, down regulation of all genes was observed during the course of the heat shock experiments. This thermally induced down regulation was particularly acute for the GRP78 gene, which at one time point was more than 100 fold down regulated. These results demonstrate the loss of the heat shock response in H. antarcticus, a basal member of the Notothenioidei. This finding is discussed with reference to the survival of Notothenioids during observed ocean warming and also the reorganisation of cellular protein mechanisms of species living in extreme environments. |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Melody S. Clark Keiron P. P. Fraser Gavin Burns Lloyd S. Peck |
author_facet |
Melody S. Clark Keiron P. P. Fraser Gavin Burns Lloyd S. Peck |
author_sort |
Melody S. Clark |
title |
HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
title_short |
HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
title_full |
HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
title_fullStr |
HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
title_full_unstemmed |
HSP_Harpagifer 1 The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus |
title_sort |
hsp_harpagifer 1 the hsp70 heat shock response in the antarctic fish harpagifer antarcticus |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.2443 http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic antarcticus |
genre_facet |
Antarc* Antarctic antarcticus |
op_source |
http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.2443 http://nora.nerc.ac.uk/3961/1/Harpy_HSP.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766269127558692864 |