CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental
marine food web for subsistence and is therefore exposed to high doses of environmental contaminants such as polychlorinated biphenyls and methylmercury and to a lesser extent lead. In view of the neurotoxic properties of these substances following developmental exposure, we initiated a study on inf...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.280.8382 2023-05-15T15:07:47+02:00 CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental Gina Muckle Pierre Ayotte Éric Dewailly Ra W. Jacobson Joseph L. Jacobson The Pennsylvania State University CiteSeerX Archives application/zip http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.8382 en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.8382 Metadata may be used without restrictions as long as the oai identifier remains attached to it. ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ee/f6/Environ_Health_Perspect_2001_Dec_109(12)_1291-1299.tar.gz text ftciteseerx 2016-01-07T21:04:27Z marine food web for subsistence and is therefore exposed to high doses of environmental contaminants such as polychlorinated biphenyls and methylmercury and to a lesser extent lead. In view of the neurotoxic properties of these substances following developmental exposure, we initiated a study on infant development in this remote coastal population. Here we report the magnitude of prenatal exposure to these contaminants and to selective nutrients in Inuit mothers and their newborns who were recruited on the Hudson Bay coast. We conducted interviews during the women’s pregnancies and at 1 and 11 months postpartum and collected biological samples for mercury, lead, polychlorinated biphenyls (PCBs), and chlorinated pesticides analyses as well as selenium and N-3 polyunsaturated fatty acids (n3-PUFA). Cord blood, maternal blood, and maternal hair mercury concentrations averaged 18.5 µg/L, 10.4 µg/L, and 3.7 µg/g, respectively, and are similar to those found in the Faroe Islands but lower than those documented in the Seychelles Islands and New Zealand cohorts. Concentrations of PCB congener 153 averaged 86.9, 105.3, and 131.6 µg/kg (lipids) in cord plasma, maternal plasma, and maternal milk, respectively; prenatal exposure to PCBs in the Nunavik cohort is similar to that reported in the Dutch but much lower than those in other Arctic cohorts. Levels of n3-PUFA in plasma phospholipids Text Arctic Faroe Islands Hudson Bay inuit Nunavik Unknown Arctic Faroe Islands Hudson Hudson Bay New Zealand Nunavik |
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marine food web for subsistence and is therefore exposed to high doses of environmental contaminants such as polychlorinated biphenyls and methylmercury and to a lesser extent lead. In view of the neurotoxic properties of these substances following developmental exposure, we initiated a study on infant development in this remote coastal population. Here we report the magnitude of prenatal exposure to these contaminants and to selective nutrients in Inuit mothers and their newborns who were recruited on the Hudson Bay coast. We conducted interviews during the women’s pregnancies and at 1 and 11 months postpartum and collected biological samples for mercury, lead, polychlorinated biphenyls (PCBs), and chlorinated pesticides analyses as well as selenium and N-3 polyunsaturated fatty acids (n3-PUFA). Cord blood, maternal blood, and maternal hair mercury concentrations averaged 18.5 µg/L, 10.4 µg/L, and 3.7 µg/g, respectively, and are similar to those found in the Faroe Islands but lower than those documented in the Seychelles Islands and New Zealand cohorts. Concentrations of PCB congener 153 averaged 86.9, 105.3, and 131.6 µg/kg (lipids) in cord plasma, maternal plasma, and maternal milk, respectively; prenatal exposure to PCBs in the Nunavik cohort is similar to that reported in the Dutch but much lower than those in other Arctic cohorts. Levels of n3-PUFA in plasma phospholipids |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Gina Muckle Pierre Ayotte Éric Dewailly Ra W. Jacobson Joseph L. Jacobson |
spellingShingle |
Gina Muckle Pierre Ayotte Éric Dewailly Ra W. Jacobson Joseph L. Jacobson CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
author_facet |
Gina Muckle Pierre Ayotte Éric Dewailly Ra W. Jacobson Joseph L. Jacobson |
author_sort |
Gina Muckle |
title |
CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
title_short |
CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
title_full |
CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
title_fullStr |
CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
title_full_unstemmed |
CHILDREN’S HEALTH Article Prenatal Exposure of the Northern Québec Inuit Infants to Environmental |
title_sort |
children’s health article prenatal exposure of the northern québec inuit infants to environmental |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.8382 |
geographic |
Arctic Faroe Islands Hudson Hudson Bay New Zealand Nunavik |
geographic_facet |
Arctic Faroe Islands Hudson Hudson Bay New Zealand Nunavik |
genre |
Arctic Faroe Islands Hudson Bay inuit Nunavik |
genre_facet |
Arctic Faroe Islands Hudson Bay inuit Nunavik |
op_source |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ee/f6/Environ_Health_Perspect_2001_Dec_109(12)_1291-1299.tar.gz |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.8382 |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766339207249264640 |