Prenatal Methylmercury Exposure and
Mercury is present in the earth's crust and is methylated by bacteria in aquatic environments to methylmercury (MeHg). It is then concentrated by the food chain so predatory fish and sea mammals have the highest levels. Thus, consuming seafood leads to exposure. MeHg readily crosses the placent...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.277.2061 2023-05-15T16:10:53+02:00 Prenatal Methylmercury Exposure and Children Neurologic Developmental Gary J. Myers Philip W. Davidson The Pennsylvania State University CiteSeerX Archives application/zip http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.2061 en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.2061 Metadata may be used without restrictions as long as the oai identifier remains attached to it. ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/b5/8d/Environ_Health_Perspect_1998_Jun_106(Suppl_3)_841-847.tar.gz Key words mercury methylmercury fetal exposure child development Seychelles neurodevelopment text ftciteseerx 2016-01-07T20:52:50Z Mercury is present in the earth's crust and is methylated by bacteria in aquatic environments to methylmercury (MeHg). It is then concentrated by the food chain so predatory fish and sea mammals have the highest levels. Thus, consuming seafood leads to exposure. MeHg readily crosses the placenta and the blood-brain barrier and is neurotoxic. The developing fetal nervous system is especially sensitive to its effects. Prenatal poisoning with high dose MeHg causes mental retardation and cerebral palsy. Lower level exposures from maternal consumption of a fish diet have not been consistently associated with adverse neurodevelopmental outcomes. However, most studies have considerable uncertainty associated with their results. Two large controlled longitudinal studies of populations consuming seafood are underway that are likely to determine if any adverse effects can be identified. No adverse associations have been found in the Seychelles, where exposure is mainly from fish consumption. In the Faroe Islands where exposure is primarily from consumption of whale meat and not fish, adverse associations have been reported. The Seychelles population consumes large amounts of marine fish containing MeHg concentrations similar to commercial fish in the United States. Current evidence does not support the hypothesis that consumption of such fish during pregnancy places the fetus at increased neurodevelopmental risk.- Environ Health Perspect 106(Suppl 3):841-847 (1998). Text Faroe Islands Unknown Faroe Islands |
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Key words mercury methylmercury fetal exposure child development Seychelles neurodevelopment |
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Key words mercury methylmercury fetal exposure child development Seychelles neurodevelopment Children Neurologic Developmental Gary J. Myers Philip W. Davidson Prenatal Methylmercury Exposure and |
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Key words mercury methylmercury fetal exposure child development Seychelles neurodevelopment |
description |
Mercury is present in the earth's crust and is methylated by bacteria in aquatic environments to methylmercury (MeHg). It is then concentrated by the food chain so predatory fish and sea mammals have the highest levels. Thus, consuming seafood leads to exposure. MeHg readily crosses the placenta and the blood-brain barrier and is neurotoxic. The developing fetal nervous system is especially sensitive to its effects. Prenatal poisoning with high dose MeHg causes mental retardation and cerebral palsy. Lower level exposures from maternal consumption of a fish diet have not been consistently associated with adverse neurodevelopmental outcomes. However, most studies have considerable uncertainty associated with their results. Two large controlled longitudinal studies of populations consuming seafood are underway that are likely to determine if any adverse effects can be identified. No adverse associations have been found in the Seychelles, where exposure is mainly from fish consumption. In the Faroe Islands where exposure is primarily from consumption of whale meat and not fish, adverse associations have been reported. The Seychelles population consumes large amounts of marine fish containing MeHg concentrations similar to commercial fish in the United States. Current evidence does not support the hypothesis that consumption of such fish during pregnancy places the fetus at increased neurodevelopmental risk.- Environ Health Perspect 106(Suppl 3):841-847 (1998). |
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The Pennsylvania State University CiteSeerX Archives |
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Text |
author |
Children Neurologic Developmental Gary J. Myers Philip W. Davidson |
author_facet |
Children Neurologic Developmental Gary J. Myers Philip W. Davidson |
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Children Neurologic Developmental |
title |
Prenatal Methylmercury Exposure and |
title_short |
Prenatal Methylmercury Exposure and |
title_full |
Prenatal Methylmercury Exposure and |
title_fullStr |
Prenatal Methylmercury Exposure and |
title_full_unstemmed |
Prenatal Methylmercury Exposure and |
title_sort |
prenatal methylmercury exposure and |
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http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.2061 |
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Faroe Islands |
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Faroe Islands |
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Faroe Islands |
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Faroe Islands |
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ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/b5/8d/Environ_Health_Perspect_1998_Jun_106(Suppl_3)_841-847.tar.gz |
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http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.2061 |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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