Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women
In the Faroe Islands in the North Atlantic, the traditional diet includes pilot whale meat and blubber and other marine food. Fatty fish and blubber of mammals may contain high concentrations of organohalogen substances (OHSs). Elevated levels of OHSs have been reported from the Faroe Islands, first...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.275.8692 2023-05-15T16:10:34+02:00 Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women Britta Fängström Maria Athanasiadou Pál Weihe Åke Bergman The Pennsylvania State University CiteSeerX Archives 2002 application/zip http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.8692 en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.8692 Metadata may be used without restrictions as long as the oai identifier remains attached to it. ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/e5/32/Environ_Health_Perspect_2002_Sep_110(9)_895-899.tar.gz text 2002 ftciteseerx 2016-01-07T20:49:27Z In the Faroe Islands in the North Atlantic, the traditional diet includes pilot whale meat and blubber and other marine food. Fatty fish and blubber of mammals may contain high concentrations of organohalogen substances (OHSs). Elevated levels of OHSs have been reported from the Faroe Islands, first documented in breast milk samples obtained in 1987. The aim of this study was to determine the concentrations of hydroxylated polychlorinated biphenyls (OH-PCBs) and polychlorinated biphenyls (PCBs) in serum samples from pregnant Faroese women known to differ in their dietary habits. High concentrations of OH-PCBs and PCBs were found in part of the human serum samples analyzed, and the relative OH-PCB and PCB congener distributions were similar to those observed elsewhere. There was a wide span between the lowest and highest OH-PCB and PCB concentrations in the serum samples analyzed, with ranges of 19–1,800 ng/g lipid weight (lw) and 150–22,000 ng/g lw, respectively. The ratio of ΣOH-PCB/ΣPCB averaged about 10 % and varied little. 4-Hydroxy-2,2´,3,4´,5,5´,6-heptachlorobiphenyl was the most abundant OH-PCB metabolite in all samples analyzed, with four other OH-PCB congeners as dominating metabolites in the serum. More than 25 additional OH-PCBs were indicated. This study confirms the presence of high concentrations of organohalogen substances in populations or areas far removed from their sources. Key words: Faroe Islands, marine foods, polychlorinated biphenyls, polychlorobiphenylols, pregnancy. Environ Health Perspect 110:895–899 (2002). [Online Text Faroe Islands North Atlantic Unknown Faroe Islands |
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In the Faroe Islands in the North Atlantic, the traditional diet includes pilot whale meat and blubber and other marine food. Fatty fish and blubber of mammals may contain high concentrations of organohalogen substances (OHSs). Elevated levels of OHSs have been reported from the Faroe Islands, first documented in breast milk samples obtained in 1987. The aim of this study was to determine the concentrations of hydroxylated polychlorinated biphenyls (OH-PCBs) and polychlorinated biphenyls (PCBs) in serum samples from pregnant Faroese women known to differ in their dietary habits. High concentrations of OH-PCBs and PCBs were found in part of the human serum samples analyzed, and the relative OH-PCB and PCB congener distributions were similar to those observed elsewhere. There was a wide span between the lowest and highest OH-PCB and PCB concentrations in the serum samples analyzed, with ranges of 19–1,800 ng/g lipid weight (lw) and 150–22,000 ng/g lw, respectively. The ratio of ΣOH-PCB/ΣPCB averaged about 10 % and varied little. 4-Hydroxy-2,2´,3,4´,5,5´,6-heptachlorobiphenyl was the most abundant OH-PCB metabolite in all samples analyzed, with four other OH-PCB congeners as dominating metabolites in the serum. More than 25 additional OH-PCBs were indicated. This study confirms the presence of high concentrations of organohalogen substances in populations or areas far removed from their sources. Key words: Faroe Islands, marine foods, polychlorinated biphenyls, polychlorobiphenylols, pregnancy. Environ Health Perspect 110:895–899 (2002). [Online |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Britta Fängström Maria Athanasiadou Pál Weihe Åke Bergman |
spellingShingle |
Britta Fängström Maria Athanasiadou Pál Weihe Åke Bergman Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
author_facet |
Britta Fängström Maria Athanasiadou Pál Weihe Åke Bergman |
author_sort |
Britta Fängström |
title |
Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
title_short |
Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
title_full |
Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
title_fullStr |
Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
title_full_unstemmed |
Articles Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women |
title_sort |
articles hydroxylated pcb metabolites and pcbs in serum from pregnant faroese women |
publishDate |
2002 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.8692 |
geographic |
Faroe Islands |
geographic_facet |
Faroe Islands |
genre |
Faroe Islands North Atlantic |
genre_facet |
Faroe Islands North Atlantic |
op_source |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/e5/32/Environ_Health_Perspect_2002_Sep_110(9)_895-899.tar.gz |
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http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.8692 |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1765995738249035776 |