ABSTRACT A method using liquid chromatography/tandem mass spectrometry (LC/MS/MS) was developed for the determination of 17α-ethynylestradiol in fish liver; a second method using LC/MS was developed for the determination of carbamazepine, diazepam, simvastatin, and oxybenzone in fish liver. The fish...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.1086.4995 2023-05-15T18:41:12+02:00 Jeong-Wook Kwon Kevin L Armbrust Doris E Vidal-Dorsch Steven M Bay Kang Xia The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1086.4995 http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1086.4995 http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf text ftciteseerx 2020-05-24T00:15:15Z ABSTRACT A method using liquid chromatography/tandem mass spectrometry (LC/MS/MS) was developed for the determination of 17α-ethynylestradiol in fish liver; a second method using LC/MS was developed for the determination of carbamazepine, diazepam, simvastatin, and oxybenzone in fish liver. The fish liver samples were extracted and cleaned up by using liquid-liquid extraction and solid-phase extraction before the extracts were analyzed by LC/MS or LC/MS/MS with electrospray negative and positive ionization. Recoveries of the five target compounds from spiked catfish liver ranged between 72 ±2% and 100 ±3%. Quantification limits for the five compounds ranged between 4.2 and 12.3 ng/g (wet weight). Ten turbot (Pleuronichthys verticalis) liver samples were analyzed; levels of 17α-ethynylestradiol, carbamazepine, simvastatin, and oxybenzone were below the detection limits. Diazepam was detected in all 10 fish liver samples at concentrations ranging between 23 and 110 ng/g (wet weight). Text Turbot Unknown |
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ftciteseerx |
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English |
description |
ABSTRACT A method using liquid chromatography/tandem mass spectrometry (LC/MS/MS) was developed for the determination of 17α-ethynylestradiol in fish liver; a second method using LC/MS was developed for the determination of carbamazepine, diazepam, simvastatin, and oxybenzone in fish liver. The fish liver samples were extracted and cleaned up by using liquid-liquid extraction and solid-phase extraction before the extracts were analyzed by LC/MS or LC/MS/MS with electrospray negative and positive ionization. Recoveries of the five target compounds from spiked catfish liver ranged between 72 ±2% and 100 ±3%. Quantification limits for the five compounds ranged between 4.2 and 12.3 ng/g (wet weight). Ten turbot (Pleuronichthys verticalis) liver samples were analyzed; levels of 17α-ethynylestradiol, carbamazepine, simvastatin, and oxybenzone were below the detection limits. Diazepam was detected in all 10 fish liver samples at concentrations ranging between 23 and 110 ng/g (wet weight). |
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The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Jeong-Wook Kwon Kevin L Armbrust Doris E Vidal-Dorsch Steven M Bay Kang Xia |
spellingShingle |
Jeong-Wook Kwon Kevin L Armbrust Doris E Vidal-Dorsch Steven M Bay Kang Xia |
author_facet |
Jeong-Wook Kwon Kevin L Armbrust Doris E Vidal-Dorsch Steven M Bay Kang Xia |
author_sort |
Jeong-Wook Kwon |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1086.4995 http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf |
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Turbot |
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Turbot |
op_source |
http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1086.4995 http://ftp.sccwrp.org/pub/download/DOCUMENTS/AnnualReports/2009AnnualReport/AR09_291_303.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766230699769069568 |