Genetic variation and population structure in native Americans.
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data avail...
Main Authors: | , , , , , |
---|---|
Other Authors: | |
Format: | Text |
Language: | English |
Published: |
2007
|
Subjects: | |
Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.2932 http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf |
id |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.1083.2932 |
---|---|
record_format |
openpolar |
spelling |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.1083.2932 2023-05-15T15:44:14+02:00 Genetic variation and population structure in native Americans. S Wang C M Lewis Jr Jr M Jakobsson S Ramachandran N Ray The Pennsylvania State University CiteSeerX Archives 2007 application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.2932 http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.2932 http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf text 2007 ftciteseerx 2020-05-03T00:28:21Z We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians-signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of differentiation between Mesoamerican and Andean populations, (3) a scenario in which coastal routes were easier for migrating peoples to traverse in comparison with inland routes, and (4) a partial agreement on a local scale between genetic similarity and the linguistic classification of populations. These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas. Text Bering Strait Unknown Bering Strait |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftciteseerx |
language |
English |
description |
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians-signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of differentiation between Mesoamerican and Andean populations, (3) a scenario in which coastal routes were easier for migrating peoples to traverse in comparison with inland routes, and (4) a partial agreement on a local scale between genetic similarity and the linguistic classification of populations. These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas. |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
S Wang C M Lewis Jr Jr M Jakobsson S Ramachandran N Ray |
spellingShingle |
S Wang C M Lewis Jr Jr M Jakobsson S Ramachandran N Ray Genetic variation and population structure in native Americans. |
author_facet |
S Wang C M Lewis Jr Jr M Jakobsson S Ramachandran N Ray |
author_sort |
S Wang |
title |
Genetic variation and population structure in native Americans. |
title_short |
Genetic variation and population structure in native Americans. |
title_full |
Genetic variation and population structure in native Americans. |
title_fullStr |
Genetic variation and population structure in native Americans. |
title_full_unstemmed |
Genetic variation and population structure in native Americans. |
title_sort |
genetic variation and population structure in native americans. |
publishDate |
2007 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.2932 http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf |
geographic |
Bering Strait |
geographic_facet |
Bering Strait |
genre |
Bering Strait |
genre_facet |
Bering Strait |
op_source |
http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.2932 http://pages.ucsd.edu/%7Erfrank/class_web/UnivHouse/pgen.0030185.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766378528993968128 |