Safety evaluation of fish protein hydrolysate supplementation in malnourished children
Safety Growth Malnutrition Children a b s t r a c t Amizate Ò is a proprietary protein hydrolysate preparation derived from Atlantic salmon (Salmo salar) using endogenous hydrolytic enzymes; it contains mostly free amino acids and short peptides, as well as small amounts of micronutrients (i.e., vit...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.1068.8513 2023-05-15T15:32:30+02:00 Safety evaluation of fish protein hydrolysate supplementation in malnourished children Knut Olav Nesse A P Nagalakshmi P Marimuthu Mamta Singh Preetida J Bhetariya Manki Ho Ryan R Simon The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1068.8513 http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1068.8513 http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf text ftciteseerx 2020-04-26T00:16:36Z Safety Growth Malnutrition Children a b s t r a c t Amizate Ò is a proprietary protein hydrolysate preparation derived from Atlantic salmon (Salmo salar) using endogenous hydrolytic enzymes; it contains mostly free amino acids and short peptides, as well as small amounts of micronutrients (i.e., vitamins and minerals). In this study, the safety of supplementation with fish protein hydrolysate (Amizate Ò ) was examined in 438 malnourished children in a randomized, placebo-controlled, double-blind, and parallel study. The children were between the ages of six to eight and met the Gomez classification for mild or moderate malnutrition. They were randomized to receive one of three interventions for four months, including a chocolate drink (control), or Amizate Ò (3 or 6 g/day) in a chocolate drink. Administration of Amizate Ò was well-tolerated, with no adverse events reported. Growth (i.e., body weight gain, changes in height, and body mass index) was not negatively impacted by administration of Amizate Ò , and routine biochemical analysis of blood and urine samples did not reveal any abnormalities that were attributable to the intervention. Findings from this study demonstrate that daily consumption of 3 or 6 g of fish protein hydrolysate (Amizate Ò ) was safe and suitable for supplementing the diets of malnourished children. Text Atlantic salmon Salmo salar Unknown Gomez ENVELOPE(-58.795,-58.795,-62.196,-62.196) |
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Unknown |
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English |
description |
Safety Growth Malnutrition Children a b s t r a c t Amizate Ò is a proprietary protein hydrolysate preparation derived from Atlantic salmon (Salmo salar) using endogenous hydrolytic enzymes; it contains mostly free amino acids and short peptides, as well as small amounts of micronutrients (i.e., vitamins and minerals). In this study, the safety of supplementation with fish protein hydrolysate (Amizate Ò ) was examined in 438 malnourished children in a randomized, placebo-controlled, double-blind, and parallel study. The children were between the ages of six to eight and met the Gomez classification for mild or moderate malnutrition. They were randomized to receive one of three interventions for four months, including a chocolate drink (control), or Amizate Ò (3 or 6 g/day) in a chocolate drink. Administration of Amizate Ò was well-tolerated, with no adverse events reported. Growth (i.e., body weight gain, changes in height, and body mass index) was not negatively impacted by administration of Amizate Ò , and routine biochemical analysis of blood and urine samples did not reveal any abnormalities that were attributable to the intervention. Findings from this study demonstrate that daily consumption of 3 or 6 g of fish protein hydrolysate (Amizate Ò ) was safe and suitable for supplementing the diets of malnourished children. |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Knut Olav Nesse A P Nagalakshmi P Marimuthu Mamta Singh Preetida J Bhetariya Manki Ho Ryan R Simon |
spellingShingle |
Knut Olav Nesse A P Nagalakshmi P Marimuthu Mamta Singh Preetida J Bhetariya Manki Ho Ryan R Simon Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
author_facet |
Knut Olav Nesse A P Nagalakshmi P Marimuthu Mamta Singh Preetida J Bhetariya Manki Ho Ryan R Simon |
author_sort |
Knut Olav Nesse |
title |
Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
title_short |
Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
title_full |
Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
title_fullStr |
Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
title_full_unstemmed |
Safety evaluation of fish protein hydrolysate supplementation in malnourished children |
title_sort |
safety evaluation of fish protein hydrolysate supplementation in malnourished children |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1068.8513 http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf |
long_lat |
ENVELOPE(-58.795,-58.795,-62.196,-62.196) |
geographic |
Gomez |
geographic_facet |
Gomez |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1068.8513 http://www.amizate-norway.com/wp-content/uploads/2014/12/Nesse-et-al-2014-published.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766362997216772096 |