Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate
a b s t r a c t The metabolic hormones, growth hormone (GH) and insulin-like growth factor (IGF)-I, together with IGF binding proteins (IGFBP), have been well studied in domestic species and are the primary components of the somatotropic axis. This hormone axis is responsive to nutrient intake, asso...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.1062.7522 2023-05-15T16:33:04+02:00 Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate Julie P Richmond Tenaya Norris Steven A Zinn The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.7522 http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.7522 http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf text ftciteseerx 2020-04-19T00:22:43Z a b s t r a c t The metabolic hormones, growth hormone (GH) and insulin-like growth factor (IGF)-I, together with IGF binding proteins (IGFBP), have been well studied in domestic species and are the primary components of the somatotropic axis. This hormone axis is responsive to nutrient intake, associated with growth rate, and accretion of protein and adipose. However, this relationship has not been evaluated in species that rely heavily on adipose stores for survival, such as pinnipeds. The primary objectives of this research were to investigate the response of the somatotropic axis to reduced nutrient intake and re-alimentation in rehabilitated harbor seal pups, and to assess if these hormones are related to nutritional status and growth rate in harbor seals. Stranded harbor seal pups (n = 24) arrived at the rehabilitation facility very thin after fasting for several days (nutritional nadir). Throughout rehabilitation nutrient intake increased and pups gained mass and body condition. Concentrations of GH and IGFBP-2 decreased with re-alimentation, while IGF-I and IGFBP-3 concentrations increased. Overall, GH and IGFBP-2 were negatively associated and IGF-I and IGFBP-3 were positively associated with growth rate and increased body condition of harbor sea pups. Further, the magnitude of the growth response was related to the magnitude in response of the somatotropic axis to varied levels of intake. These data suggest that multiple components of the somatotropic axis may be used to assess the energy status of individuals and may also provide information on the level of feed intake that is predictive of growth rate. Text harbor seal Unknown |
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a b s t r a c t The metabolic hormones, growth hormone (GH) and insulin-like growth factor (IGF)-I, together with IGF binding proteins (IGFBP), have been well studied in domestic species and are the primary components of the somatotropic axis. This hormone axis is responsive to nutrient intake, associated with growth rate, and accretion of protein and adipose. However, this relationship has not been evaluated in species that rely heavily on adipose stores for survival, such as pinnipeds. The primary objectives of this research were to investigate the response of the somatotropic axis to reduced nutrient intake and re-alimentation in rehabilitated harbor seal pups, and to assess if these hormones are related to nutritional status and growth rate in harbor seals. Stranded harbor seal pups (n = 24) arrived at the rehabilitation facility very thin after fasting for several days (nutritional nadir). Throughout rehabilitation nutrient intake increased and pups gained mass and body condition. Concentrations of GH and IGFBP-2 decreased with re-alimentation, while IGF-I and IGFBP-3 concentrations increased. Overall, GH and IGFBP-2 were negatively associated and IGF-I and IGFBP-3 were positively associated with growth rate and increased body condition of harbor sea pups. Further, the magnitude of the growth response was related to the magnitude in response of the somatotropic axis to varied levels of intake. These data suggest that multiple components of the somatotropic axis may be used to assess the energy status of individuals and may also provide information on the level of feed intake that is predictive of growth rate. |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Julie P Richmond Tenaya Norris Steven A Zinn |
spellingShingle |
Julie P Richmond Tenaya Norris Steven A Zinn Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
author_facet |
Julie P Richmond Tenaya Norris Steven A Zinn |
author_sort |
Julie P Richmond |
title |
Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
title_short |
Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
title_full |
Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
title_fullStr |
Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
title_full_unstemmed |
Re-alimentation in harbor seal pups: Effects on the somatotropic axis and growth rate |
title_sort |
re-alimentation in harbor seal pups: effects on the somatotropic axis and growth rate |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.7522 http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf |
genre |
harbor seal |
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harbor seal |
op_source |
http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.7522 http://www.marinemammalcenter.org/assets/pdfs/vetsci-stranding/scientific-contributions/2010/re-alimentation-in-harbor.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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1766022791856914432 |