Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin
ajpregu.00011.2002.—This study tests the hypothesis that the metabolic and endocrine shift characterizing the phase II-phase III transition during prolonged fasting is related to a decrease in fatty acid (FA) oxidation. Changes in plasma concentrations of various metabolites and hormones and in lipo...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.1032.1137 2023-05-15T17:03:55+02:00 Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin Servane F. Bernard Eliane Mioskowski Rene ́ Groscolas Am J Physiol Regulatory Integrative Comp Physiol The Pennsylvania State University CiteSeerX Archives 2002 application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1032.1137 http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1032.1137 http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf text 2002 ftciteseerx 2016-10-30T00:14:19Z ajpregu.00011.2002.—This study tests the hypothesis that the metabolic and endocrine shift characterizing the phase II-phase III transition during prolonged fasting is related to a decrease in fatty acid (FA) oxidation. Changes in plasma concentrations of various metabolites and hormones and in lipolytic fluxes, as determined by continuous infusion of [2-3H]glycerol and [1-14C]palmitate, were examined in vivo in spontaneously fasting king penguins in the phase II status (large fat stores, protein sparing) before, during, and after treatment with mercaptoacetate (MA), an inhibitor of FA oxidation. MA induced a 7-fold decrease in plasma -hy-droxybutyrate and a 2- to 2.5-fold increase in plasma nones-terified fatty acids (NEFA), glycerol, and triacylglycerols. MA also stimulated lipolytic fluxes, increasing the rate of appear-ance of NEFA and glycerol by 60–90%. This stimulation Text King Penguins Unknown |
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English |
description |
ajpregu.00011.2002.—This study tests the hypothesis that the metabolic and endocrine shift characterizing the phase II-phase III transition during prolonged fasting is related to a decrease in fatty acid (FA) oxidation. Changes in plasma concentrations of various metabolites and hormones and in lipolytic fluxes, as determined by continuous infusion of [2-3H]glycerol and [1-14C]palmitate, were examined in vivo in spontaneously fasting king penguins in the phase II status (large fat stores, protein sparing) before, during, and after treatment with mercaptoacetate (MA), an inhibitor of FA oxidation. MA induced a 7-fold decrease in plasma -hy-droxybutyrate and a 2- to 2.5-fold increase in plasma nones-terified fatty acids (NEFA), glycerol, and triacylglycerols. MA also stimulated lipolytic fluxes, increasing the rate of appear-ance of NEFA and glycerol by 60–90%. This stimulation |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Servane F. Bernard Eliane Mioskowski Rene ́ Groscolas Am J Physiol Regulatory Integrative Comp Physiol |
spellingShingle |
Servane F. Bernard Eliane Mioskowski Rene ́ Groscolas Am J Physiol Regulatory Integrative Comp Physiol Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
author_facet |
Servane F. Bernard Eliane Mioskowski Rene ́ Groscolas Am J Physiol Regulatory Integrative Comp Physiol |
author_sort |
Servane F. Bernard |
title |
Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
title_short |
Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
title_full |
Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
title_fullStr |
Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
title_full_unstemmed |
Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin |
title_sort |
blockade of fatty acid oxidation mimics phase ii-phase iii transition in a fasting bird, the king penguin |
publishDate |
2002 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1032.1137 http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf |
genre |
King Penguins |
genre_facet |
King Penguins |
op_source |
http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1032.1137 http://ajpregu.physiology.org/content/ajpregu/283/1/R144.full.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766057918602412032 |