Vitamin D supplementation during Antarctic winter
Background: Persons with limited exposure to ultraviolet B light, including space travelers, may not receive enough vitamin D. Recent studies indicate that optimal serum 25-hydroxyvitamin D [25(OH)D] should be 80 nmol/L. Objective: This study was designed to evaluate the effectiveness of 3 doses of...
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Text |
Language: | English |
Subjects: | |
Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1100 http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf |
id |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.1028.1100 |
---|---|
record_format |
openpolar |
spelling |
ftciteseerx:oai:CiteSeerX.psu:10.1.1.1028.1100 2023-05-15T13:44:16+02:00 Vitamin D supplementation during Antarctic winter Scott M Smith Keri K Gardner James Locke Sara R Zwart The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1100 http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1100 http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf text ftciteseerx 2016-10-30T00:05:41Z Background: Persons with limited exposure to ultraviolet B light, including space travelers, may not receive enough vitamin D. Recent studies indicate that optimal serum 25-hydroxyvitamin D [25(OH)D] should be 80 nmol/L. Objective: This study was designed to evaluate the effectiveness of 3 doses of vitamin D to raise and maintain 25(OH)D to a con-centration.80 nmol/L in persons with limited ultraviolet B light exposure. Design: This was a 5-mo prospective, randomized, double-blind study of vitamin D supplementation. It was conducted during winter in Antarctica at the McMurdo Station, when ultraviolet B radiation levels are essentially zero. The 55 subjects were randomly divided into 3 groups for vitamin D supplementation: 2000 IU/d (n 18), 1000 IU/d (n 19), and 400 IU/d (n 18). An additional 7 subjects did not take supplements or took supplements of their own choos-ing. Blood samples were collected about every 2 mo during the winter. Results: About 5 mo after supplementation started, 25(OH)D increased to 71 6 23 nmol/L in the 2000-IU/d group, 63 6 25 nmol/L in the 1000-IU/d group, and 57 6 15 nmol/L in the 400-IU/d group and decreased to 34 6 12 nmol/L in the group not taking supplements. Conclusions: These data will enable us to provide space crews with evidence-based recommendations for vitamin D supplemen-tation. The findings also have implications for other persons with limited ultraviolet light exposure, including polar workers and the elderly. Am J Clin Nutr 2009;89:1–7. Text Antarc* Antarctic Antarctica Unknown Antarctic McMurdo Station ENVELOPE(166.667,166.667,-77.850,-77.850) |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftciteseerx |
language |
English |
description |
Background: Persons with limited exposure to ultraviolet B light, including space travelers, may not receive enough vitamin D. Recent studies indicate that optimal serum 25-hydroxyvitamin D [25(OH)D] should be 80 nmol/L. Objective: This study was designed to evaluate the effectiveness of 3 doses of vitamin D to raise and maintain 25(OH)D to a con-centration.80 nmol/L in persons with limited ultraviolet B light exposure. Design: This was a 5-mo prospective, randomized, double-blind study of vitamin D supplementation. It was conducted during winter in Antarctica at the McMurdo Station, when ultraviolet B radiation levels are essentially zero. The 55 subjects were randomly divided into 3 groups for vitamin D supplementation: 2000 IU/d (n 18), 1000 IU/d (n 19), and 400 IU/d (n 18). An additional 7 subjects did not take supplements or took supplements of their own choos-ing. Blood samples were collected about every 2 mo during the winter. Results: About 5 mo after supplementation started, 25(OH)D increased to 71 6 23 nmol/L in the 2000-IU/d group, 63 6 25 nmol/L in the 1000-IU/d group, and 57 6 15 nmol/L in the 400-IU/d group and decreased to 34 6 12 nmol/L in the group not taking supplements. Conclusions: These data will enable us to provide space crews with evidence-based recommendations for vitamin D supplemen-tation. The findings also have implications for other persons with limited ultraviolet light exposure, including polar workers and the elderly. Am J Clin Nutr 2009;89:1–7. |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Scott M Smith Keri K Gardner James Locke Sara R Zwart |
spellingShingle |
Scott M Smith Keri K Gardner James Locke Sara R Zwart Vitamin D supplementation during Antarctic winter |
author_facet |
Scott M Smith Keri K Gardner James Locke Sara R Zwart |
author_sort |
Scott M Smith |
title |
Vitamin D supplementation during Antarctic winter |
title_short |
Vitamin D supplementation during Antarctic winter |
title_full |
Vitamin D supplementation during Antarctic winter |
title_fullStr |
Vitamin D supplementation during Antarctic winter |
title_full_unstemmed |
Vitamin D supplementation during Antarctic winter |
title_sort |
vitamin d supplementation during antarctic winter |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1100 http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf |
long_lat |
ENVELOPE(166.667,166.667,-77.850,-77.850) |
geographic |
Antarctic McMurdo Station |
geographic_facet |
Antarctic McMurdo Station |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_source |
http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1028.1100 http://ajcn.nutrition.org/content/early/2009/02/18/ajcn.2008.27189.full.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766199563031412736 |