Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal-ventral patterning in the mollusk Crassostrea gigas

• Published in: Development Genes and Evolution
• Main Authors: Tan, Sujian, Huan, Pin, Liu, Baozhong
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2017
• Subjects: Axis; Bmp2/4; Chordin; Dorsal-ventral; Mollusk; Leech; Crassostrea gigas
• Online Access: http://ir.qdio.ac.cn/handle/337002/136741; https://doi.org/10.1007/s00427-016-0570-3

Though several bilaterian animals use a conserved BMP2/4-Chordin antagonism to pattern the dorsal-ventral (DV) axis, the only lophotrochozoan species in which early DV patterning has been studied to date, the leech Helobdella robusta, appears to employ BMP5-8 and Gremlin. These findings call into qu...