Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus)
QTL is a chromosomal region including single gene or gene clusters that determine a quantitative trait. While feed efficiency is highly important in aquaculture fish, little genetic and genomic progresses have been made for this trait. In this study, we constructed a high-resolution genetic linkage...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , , , , , |
Format: | Report |
Language: | English |
Published: |
NATURE PUBLISHING GROUP
2017
|
Subjects: | |
Online Access: | http://ir.ihb.ac.cn/handle/342005/30705 https://doi.org/10.1038/s41598-017-17269-2 |
id |
ftchinacadsciihb:oai:ir.ihb.ac.cn:342005/30705 |
---|---|
record_format |
openpolar |
spelling |
ftchinacadsciihb:oai:ir.ihb.ac.cn:342005/30705 2023-05-15T18:09:56+02:00 Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) Pang, Meixia Fu, Beide Yu, Xiaomu Liu, Haiyang Wang, Xinhua Yin, Zhan Xie, Shouqi Tong, Jingou 2017-12-05 http://ir.ihb.ac.cn/handle/342005/30705 https://doi.org/10.1038/s41598-017-17269-2 英语 eng NATURE PUBLISHING GROUP SCIENTIFIC REPORTS http://ir.ihb.ac.cn/handle/342005/30705 doi:10.1038/s41598-017-17269-2 Science & Technology - Other Topics Multidisciplinary Sciences TROUT ONCORHYNCHUS-MYKISS CHARR SALVELINUS-ALPINUS GENOME-WIDE ASSOCIATION SALMON SALMO-SALAR BEEF-CATTLE BODY-WEIGHT GENETIC ARCHITECTURE RAINBOW-TROUT METHANE PRODUCTION SEXUAL-MATURATION 期刊论文 2017 ftchinacadsciihb https://doi.org/10.1038/s41598-017-17269-2 2019-07-12T00:04:07Z QTL is a chromosomal region including single gene or gene clusters that determine a quantitative trait. While feed efficiency is highly important in aquaculture fish, little genetic and genomic progresses have been made for this trait. In this study, we constructed a high-resolution genetic linkage map in a full-sib F1 family of crucian carp (Carassius auratus) consisting of 113 progenies with 8,460 SNP markers assigning onto 50 linkage groups (LGs). This genetic map spanned 4,047.824 cM (0.478 cM/marker) and covered 98.76% of the crucian carp genome. 35 chromosome-wide QTL affecting feed conversion efficiency (FCE, 8 QTL), relative growth rate (RGR, 9 QTL), average daily gain (ADG, 13 QTL) and average daily feed intake (ADFI, 5 QTL) were detected on 14 LGs, explaining 14.0-20.9% of the phenotypic variations. In LGs of LG16, LG25, LG36 and LG49, several QTL affecting different traits clustered together at the identical or close regions of the same linkage group. Seven candidate genes, whose biological functions may involve in the energy metabolism, digestion, biosynthesis and signal transduction, were identified from these QTL intervals by comparative genomics analysis. These results provide a basis for elucidating genetic mechanism of feed efficiency and potential marker-assisted selection in crucian carp. Report Salmo salar Salvelinus alpinus Institute of Hydrobiology, Chinese Academy of Sciences: IHB OpenIR Scientific Reports 7 1 |
institution |
Open Polar |
collection |
Institute of Hydrobiology, Chinese Academy of Sciences: IHB OpenIR |
op_collection_id |
ftchinacadsciihb |
language |
English |
topic |
Science & Technology - Other Topics Multidisciplinary Sciences TROUT ONCORHYNCHUS-MYKISS CHARR SALVELINUS-ALPINUS GENOME-WIDE ASSOCIATION SALMON SALMO-SALAR BEEF-CATTLE BODY-WEIGHT GENETIC ARCHITECTURE RAINBOW-TROUT METHANE PRODUCTION SEXUAL-MATURATION |
spellingShingle |
Science & Technology - Other Topics Multidisciplinary Sciences TROUT ONCORHYNCHUS-MYKISS CHARR SALVELINUS-ALPINUS GENOME-WIDE ASSOCIATION SALMON SALMO-SALAR BEEF-CATTLE BODY-WEIGHT GENETIC ARCHITECTURE RAINBOW-TROUT METHANE PRODUCTION SEXUAL-MATURATION Pang, Meixia Fu, Beide Yu, Xiaomu Liu, Haiyang Wang, Xinhua Yin, Zhan Xie, Shouqi Tong, Jingou Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
topic_facet |
Science & Technology - Other Topics Multidisciplinary Sciences TROUT ONCORHYNCHUS-MYKISS CHARR SALVELINUS-ALPINUS GENOME-WIDE ASSOCIATION SALMON SALMO-SALAR BEEF-CATTLE BODY-WEIGHT GENETIC ARCHITECTURE RAINBOW-TROUT METHANE PRODUCTION SEXUAL-MATURATION |
description |
QTL is a chromosomal region including single gene or gene clusters that determine a quantitative trait. While feed efficiency is highly important in aquaculture fish, little genetic and genomic progresses have been made for this trait. In this study, we constructed a high-resolution genetic linkage map in a full-sib F1 family of crucian carp (Carassius auratus) consisting of 113 progenies with 8,460 SNP markers assigning onto 50 linkage groups (LGs). This genetic map spanned 4,047.824 cM (0.478 cM/marker) and covered 98.76% of the crucian carp genome. 35 chromosome-wide QTL affecting feed conversion efficiency (FCE, 8 QTL), relative growth rate (RGR, 9 QTL), average daily gain (ADG, 13 QTL) and average daily feed intake (ADFI, 5 QTL) were detected on 14 LGs, explaining 14.0-20.9% of the phenotypic variations. In LGs of LG16, LG25, LG36 and LG49, several QTL affecting different traits clustered together at the identical or close regions of the same linkage group. Seven candidate genes, whose biological functions may involve in the energy metabolism, digestion, biosynthesis and signal transduction, were identified from these QTL intervals by comparative genomics analysis. These results provide a basis for elucidating genetic mechanism of feed efficiency and potential marker-assisted selection in crucian carp. |
format |
Report |
author |
Pang, Meixia Fu, Beide Yu, Xiaomu Liu, Haiyang Wang, Xinhua Yin, Zhan Xie, Shouqi Tong, Jingou |
author_facet |
Pang, Meixia Fu, Beide Yu, Xiaomu Liu, Haiyang Wang, Xinhua Yin, Zhan Xie, Shouqi Tong, Jingou |
author_sort |
Pang, Meixia |
title |
Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
title_short |
Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
title_full |
Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
title_fullStr |
Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
title_full_unstemmed |
Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus) |
title_sort |
quantitative trait loci mapping for feed conversion efficiency in crucian carp (carassius auratus) |
publisher |
NATURE PUBLISHING GROUP |
publishDate |
2017 |
url |
http://ir.ihb.ac.cn/handle/342005/30705 https://doi.org/10.1038/s41598-017-17269-2 |
genre |
Salmo salar Salvelinus alpinus |
genre_facet |
Salmo salar Salvelinus alpinus |
op_relation |
SCIENTIFIC REPORTS http://ir.ihb.ac.cn/handle/342005/30705 doi:10.1038/s41598-017-17269-2 |
op_doi |
https://doi.org/10.1038/s41598-017-17269-2 |
container_title |
Scientific Reports |
container_volume |
7 |
container_issue |
1 |
_version_ |
1766182635212636160 |