慢性腎不全における酸塩基平衡に関する臨床的研究
In order to study acid-base balance in chronic renal failure, the variations of the bicarbonate-carbonic acid buffer system, chloride, HPO_4^<-->, SO_4^<--> and potassium were analysed. The results obtained are as follows. Use of venous blood was useful clinically to determine blood pH a...
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千葉医学会
1969
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ftchibauniv:oai:opac.ll.chiba-u.jp:900114683 2024-02-11T10:02:52+01:00 慢性腎不全における酸塩基平衡に関する臨床的研究 Clinical Studies on Acid-Base Balance in Chronic Renal Failure 原著 Original Article 鈴木,光 SUZUKI,AKIRA 千葉大学医学部第一内科学教室 dateofissued:1969 application/pdf https://opac.ll.chiba-u.jp/da/curator/900114683/ https://opac.ll.chiba-u.jp/da/curator/900114683/KJ00005678432.pdf jpn jpn 千葉医学会 ISSN:0009-3459 NCID:AN00142206 jtitle:千葉医学会雑誌 = The Journal of Chiba Medical Society volume:44 issue:6 spage:904 epage:919 https://opac.ll.chiba-u.jp/da/curator/900114683/ https://opac.ll.chiba-u.jp/da/curator/900114683/KJ00005678432.pdf Journal Article text 1969 ftchibauniv 2024-01-16T06:33:01Z In order to study acid-base balance in chronic renal failure, the variations of the bicarbonate-carbonic acid buffer system, chloride, HPO_4^<-->, SO_4^<--> and potassium were analysed. The results obtained are as follows. Use of venous blood was useful clinically to determine blood pH and Pco_2. In chronic renal failure, reduction in pH was usually seen before respiratory disorder, such as Kussmaul's breathing, became evident. Such pH reduction was caused by insufficient decrease of Pco_2 comparing with HGO_3^-. HPO4〜〜 and SO_4^<--> had positive correlation with BUN, and when HPO_4^<--> and SO_4^<--> elevated, low HCO_3^- was observed. Therefore, if we consider acidosis as a major purpose for hemodialysis, elevation of BUN is a useful index to indicate hemodialysis. It was suggested that low blood HCO_3^- was not the direct result of elevation of HPO_4^<--> and SO_4^<-->. Hypochloremia in chronic renal failure is due mostly to the reduction in HCO_3^<-->, and hypoproteinemia accentuates it. Marked elevations of HPO_4^<--> and SO_4^<--> were observed in hypochloremia of chronic renal failure in our study. However, these elevations could not be so large in the patients, other factors are to be checked when severe hypochloremia is seen. Body potassium reduction was observed in terminal stage of chronic renal failure. Decrease in pH was found to influence blood potassium level if hyperkalemia was found in terminal stage. Article in Journal/Newspaper Carbonic acid CURATOR - Chiba University Repository for Access to Outcomes from Research |
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CURATOR - Chiba University Repository for Access to Outcomes from Research |
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ftchibauniv |
language |
Japanese |
description |
In order to study acid-base balance in chronic renal failure, the variations of the bicarbonate-carbonic acid buffer system, chloride, HPO_4^<-->, SO_4^<--> and potassium were analysed. The results obtained are as follows. Use of venous blood was useful clinically to determine blood pH and Pco_2. In chronic renal failure, reduction in pH was usually seen before respiratory disorder, such as Kussmaul's breathing, became evident. Such pH reduction was caused by insufficient decrease of Pco_2 comparing with HGO_3^-. HPO4〜〜 and SO_4^<--> had positive correlation with BUN, and when HPO_4^<--> and SO_4^<--> elevated, low HCO_3^- was observed. Therefore, if we consider acidosis as a major purpose for hemodialysis, elevation of BUN is a useful index to indicate hemodialysis. It was suggested that low blood HCO_3^- was not the direct result of elevation of HPO_4^<--> and SO_4^<-->. Hypochloremia in chronic renal failure is due mostly to the reduction in HCO_3^<-->, and hypoproteinemia accentuates it. Marked elevations of HPO_4^<--> and SO_4^<--> were observed in hypochloremia of chronic renal failure in our study. However, these elevations could not be so large in the patients, other factors are to be checked when severe hypochloremia is seen. Body potassium reduction was observed in terminal stage of chronic renal failure. Decrease in pH was found to influence blood potassium level if hyperkalemia was found in terminal stage. |
author2 |
千葉大学医学部第一内科学教室 |
format |
Article in Journal/Newspaper |
author |
鈴木,光 SUZUKI,AKIRA |
spellingShingle |
鈴木,光 SUZUKI,AKIRA 慢性腎不全における酸塩基平衡に関する臨床的研究 |
author_facet |
鈴木,光 SUZUKI,AKIRA |
author_sort |
鈴木,光 |
title |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
title_short |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
title_full |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
title_fullStr |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
title_full_unstemmed |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
title_sort |
慢性腎不全における酸塩基平衡に関する臨床的研究 |
publisher |
千葉医学会 |
publishDate |
1969 |
url |
https://opac.ll.chiba-u.jp/da/curator/900114683/ https://opac.ll.chiba-u.jp/da/curator/900114683/KJ00005678432.pdf |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_relation |
ISSN:0009-3459 NCID:AN00142206 jtitle:千葉医学会雑誌 = The Journal of Chiba Medical Society volume:44 issue:6 spage:904 epage:919 https://opac.ll.chiba-u.jp/da/curator/900114683/ https://opac.ll.chiba-u.jp/da/curator/900114683/KJ00005678432.pdf |
_version_ |
1790598959564062720 |