Infectious pancreatic necrosis virus induces apoptosis in vitro and in vivo independent of VP5 expression

• Published in: Virology
• Main Authors: Santi, Nina, Sandtro, Ane, Sindre, Hilde, Song, Haichen, Hong, Jiann-Ruey, Thu, Beate, Wu, Jen-Leih, Vakharia, Jen-Leih, Evensen, ystein
• Other Authors: Institute of Biotechnology
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2005
• Subjects: IPNV; VP5; apoptosis; Bcl-2; Evensen; Atlantic salmon
• Online Access: https://doi.org/10.1016/j.virol.2005.07.028; http://ir.lib.ncku.edu.tw/handle/987654321/83536

Infectious pancreatic necrosis virus (IPNV), the causative agent of a highly infectious disease in salmonid fish, encodes a small nonstructural protein designated VP5. This protein contains Bcl-2 homologous domains and inhibits apoptosis when expressed in cell culture. We have previously reported th...