Archaic Adaptive Introgression in TBX15/WARS2

A recent study conducted the first genome-wide scan for selection in Inuit from Greenland using single nucleotide polymorphism chip data. Here, we report that selection in the region with the second most extreme signal of positive selection in Greenlandic Inuit favored a deeply divergent haplotype t...

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Bibliographic Details
Main Authors: Racimo, Fernando, Gokhman, David, Fumagalli, Matteo, Ko, Amy, Hansen, Torben, Moltke, Ida, Albrechtsen, Anders, Carmel, Liran, Huerta-Sánchez, Emilia, Nielsen, Rasmus
Format: Article in Journal/Newspaper
Language:unknown
Published: eScholarship, University of California 2017
Subjects:
Human Genome
Genetics
Underpinning research
1.1 Normal biological development and functioning
Generic health relevance
Adaptation
Biological
Adipose Tissue
Alleles
Animals
DNA Methylation
DNA
Ancient
Greenland
Haplotypes
Humans
Inuit
Models
Genetic
Neanderthals
Polymorphism
Single Nucleotide
Selection
Sequence Analysis
T-Box Domain Proteins
adaptive introgression
Denisova
positive selection
Native Americans
methylation
admixture
Biochemistry and Cell Biology
Evolutionary Biology
greenlandic
inuit
Online Access:https://escholarship.org/uc/item/4nk8v86h

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