A reservoir of ‘historical’ antibiotic resistance genes in remote pristine Antarctic soils

• Main Authors: Van Goethem, Marc W, Pierneef, Rian, Bezuidt, Oliver KI, Van De Peer, Yves, Cowan, Don A, Makhalanyane, Thulani P
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: eScholarship, University of California 2018
• Subjects: Genetics; Infectious Diseases; Antimicrobial Resistance; Infection; Life Below Water; Antarctic Regions; Anti-Bacterial Agents; Bacteria; Drug Resistance; Multiple; Bacterial; Gene Transfer; Horizontal; Genes; Membrane Transport Proteins; Metagenomics; Soil Microbiology; Antibiotic resistance genes; Soil resistome; Antarctica; Ecology; Microbiology; Medical Microbiology; Antarctic; Mackay; Mackay Glacier; Antarc*
• Online Access: https://escholarship.org/uc/item/4kn746f2

BackgroundSoil bacteria naturally produce antibiotics as a competitive mechanism, with a concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic resistance mechanisms. Surveys of bacterial resistance elements in edaphic systems have originated primarily from human-i...