Exploring Cold-Adapted Eye Lens Proteins and Discovery of an Antimicrobial Protein from a Carnivorous Plant

• Main Author: Bierma, Jan
• Other Authors: Martin, Rachel W
• Format: Other/Unknown Material
• Language: English
• Published: eScholarship, University of California 2019
• Subjects: Biochemistry; Biophysics; carnivorous plant; cold-adaptation; crystallin; membrane protein; phase separation; Antarctic; Psi; The Antarctic; Antarc*; Antarctic Toothfish
• Online Access: https://escholarship.org/uc/item/9pj2j88f

This thesis explores the eye lens proteins from the Antarctic toothfish Dissostichus mawsoni and how they have evolved to the subfreezing temperatures of their environment. This includes showing that toothfish γS1- and γS2-crystallins are less stable than their homologous human counterparts and work...