The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease.
This study aimed to characterize the histological, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of the domestic dog in health and disease. In addition, we sought to identify structure-function relationships and to characterize TMJ degenerative lesions that may be fou...
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ftcdlib:oai:escholarship.org/ark:/13030/qt6861n98z 2023-05-15T15:51:17+02:00 The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. Lin, AW Vapniarsky, N Cissell, DD Verstraete, FJM Lin, CH Hatcher, DC Arzi, B 2018-05-01 application/pdf https://escholarship.org/uc/item/6861n98z unknown eScholarship, University of California qt6861n98z https://escholarship.org/uc/item/6861n98z public Temporomandibular Joint Animals Dogs Temporomandibular Joint Disorders Dog Diseases cartilage dog osteoarthritis temporomandibular joint degeneration Veterinary Sciences article 2018 ftcdlib 2021-07-05T17:08:15Z This study aimed to characterize the histological, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of the domestic dog in health and disease. In addition, we sought to identify structure-function relationships and to characterize TMJ degenerative lesions that may be found naturally in this species. TMJs (n=20) from fresh cadaver heads (n=10) of domestic dogs were examined macroscopically and microscopicallyand by cone-beam computed tomography. The TMJ discs were evaluated for their mechanical and biochemical properties. If TMJ arthritic changes were found, pathological characteristics weredescribed and compared with healthy joints. Five (50%) dogs demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs and five (50%) dogs exhibited degenerative changes that were observed either in the articular surfaces or the discs. In the articulating surfaces, these changes included erosions, conformational changes and osteophytes. In the discs, degenerative changes were represented by full-thickness perforations. Histologically, pathological specimens demonstrated fibrillations with or without erosions, subchondral bone defects and subchondral bone sclerosis. Significant anisotropy in the TMJ discs was evident on histology and tensile mechanical testing. Specifically, the discs were significantly stiffer and stronger in the rostrocaudal direction compared with the mediolateral direction. No significant differences were detected in compressive properties of different disc regions. Biochemical analyses showed high collagen content and low glycosaminoglycan (GAG) content. No significant differences in biochemical composition, apart from GAG, were detected among the disc regions. GAG concentration was significantly higher in the central region as compared with the caudal (posterior) region. The TMJ of the domestic dog exhibits similarities, but also differences, compared with other mammals with regards to structure-function relationships. The TMJ articular surfaces and the disc exhibit degenerative changes as seen in other species, including perforation of the disc as seen in man. The degenerative changes had greater effects on the mechanical properties compared with the biochemical properties of the TMJ components. Translational motion of the TMJ does occur in dogs, but is limited. Article in Journal/Newspaper Canis lupus University of California: eScholarship |
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Open Polar |
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University of California: eScholarship |
op_collection_id |
ftcdlib |
language |
unknown |
topic |
Temporomandibular Joint Animals Dogs Temporomandibular Joint Disorders Dog Diseases cartilage dog osteoarthritis temporomandibular joint degeneration Veterinary Sciences |
spellingShingle |
Temporomandibular Joint Animals Dogs Temporomandibular Joint Disorders Dog Diseases cartilage dog osteoarthritis temporomandibular joint degeneration Veterinary Sciences Lin, AW Vapniarsky, N Cissell, DD Verstraete, FJM Lin, CH Hatcher, DC Arzi, B The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
topic_facet |
Temporomandibular Joint Animals Dogs Temporomandibular Joint Disorders Dog Diseases cartilage dog osteoarthritis temporomandibular joint degeneration Veterinary Sciences |
description |
This study aimed to characterize the histological, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of the domestic dog in health and disease. In addition, we sought to identify structure-function relationships and to characterize TMJ degenerative lesions that may be found naturally in this species. TMJs (n=20) from fresh cadaver heads (n=10) of domestic dogs were examined macroscopically and microscopicallyand by cone-beam computed tomography. The TMJ discs were evaluated for their mechanical and biochemical properties. If TMJ arthritic changes were found, pathological characteristics weredescribed and compared with healthy joints. Five (50%) dogs demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs and five (50%) dogs exhibited degenerative changes that were observed either in the articular surfaces or the discs. In the articulating surfaces, these changes included erosions, conformational changes and osteophytes. In the discs, degenerative changes were represented by full-thickness perforations. Histologically, pathological specimens demonstrated fibrillations with or without erosions, subchondral bone defects and subchondral bone sclerosis. Significant anisotropy in the TMJ discs was evident on histology and tensile mechanical testing. Specifically, the discs were significantly stiffer and stronger in the rostrocaudal direction compared with the mediolateral direction. No significant differences were detected in compressive properties of different disc regions. Biochemical analyses showed high collagen content and low glycosaminoglycan (GAG) content. No significant differences in biochemical composition, apart from GAG, were detected among the disc regions. GAG concentration was significantly higher in the central region as compared with the caudal (posterior) region. The TMJ of the domestic dog exhibits similarities, but also differences, compared with other mammals with regards to structure-function relationships. The TMJ articular surfaces and the disc exhibit degenerative changes as seen in other species, including perforation of the disc as seen in man. The degenerative changes had greater effects on the mechanical properties compared with the biochemical properties of the TMJ components. Translational motion of the TMJ does occur in dogs, but is limited. |
format |
Article in Journal/Newspaper |
author |
Lin, AW Vapniarsky, N Cissell, DD Verstraete, FJM Lin, CH Hatcher, DC Arzi, B |
author_facet |
Lin, AW Vapniarsky, N Cissell, DD Verstraete, FJM Lin, CH Hatcher, DC Arzi, B |
author_sort |
Lin, AW |
title |
The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
title_short |
The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
title_full |
The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
title_fullStr |
The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
title_full_unstemmed |
The Temporomandibular Joint of the Domestic Dog (Canis lupus familiaris) in Health and Disease. |
title_sort |
temporomandibular joint of the domestic dog (canis lupus familiaris) in health and disease. |
publisher |
eScholarship, University of California |
publishDate |
2018 |
url |
https://escholarship.org/uc/item/6861n98z |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
qt6861n98z https://escholarship.org/uc/item/6861n98z |
op_rights |
public |
_version_ |
1766386437019664384 |