Emergence of Arctic-like Rabies Lineage in India

• Other Authors: Nadin-Davis, Susan A., Turner, Geoff, Paul, Joel P. V., Madhusudana, Shampur N., Wandeler, Alexander I.
• Language: English
• Subjects: Research; Adolescent; Adult; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Child; Dog Diseases; Dogs; Female; Humans; Male; Nucleocapsid Proteins; Phylogeny; Rabies; Rabies virus; Saliva; Arctic; Indian
• Online Access: https://stacks.cdc.gov/view/cdc/16410

A collection of 37 rabies-infected samples, 10 human saliva and 27 animal brain, were recovered during 2001-2004 from the cities of Bangalore and Hyderabad in southern India and from Kasauli, a mountainous region in Himachal Pradesh, northern India. Phylogenetic analysis of partial N gene nucleotide sequences of these 37 specimens and 1 archival specimen identified 2 groups, divided according to their geographic (north or south) origins. Comparison of selected Indian viruses with representative rabies viruses recovered worldwide showed a close association of all Indian isolates with the circumpolar Arctic rabies lineage distributed throughout northern latitudes of North America and Europe and other viruses recovered from several Asian countries.