Seroprevalence dynamics of European bat lyssavirus type 1 in a multispecies bat colony.

• Published in: Viruses
• Main Authors: López-Roig, Marc, Bourhy, Hervé, Lavenir, Rachel, Serra-Cobo, Jordi
• Other Authors: Departament de Biologia Animal, Universitat de Barcelona (UB), Centre Collaborateur de l'OMS pour la Rage - Dynamique des lyssavirus et adaptation à l'hôte (CC-OMS), Institut Pasteur Paris, Department of Animal Biology (Institute for Research on Biodiversity (IRBio)), University of Barcelona, Ministerio de Sanidad y Servicios Sociales e Igualdad, Dirección General de Salud Pública y Sanidad Exterior, European Project: 34247,RABMEDCONTROL, European Project: 278433,EC:FP7:HEALTH,FP7-HEALTH-2011-two-stage,PREDEMICS(2011)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2014
• Subjects: bats; EBLV-1; Iberian Peninsula; Lyssavirus; prevalence; serology; temporal variation; MESH: Animal Diseases; MESH: Animals; MESH: Male; MESH: Rhabdoviridae Infections; MESH: Seroepidemiologic Studies; MESH: Spatio-Temporal Analysis; MESH: Antibodies; Neutralizing; Viral; MESH: Biodiversity; MESH: Chiroptera; MESH: Female; MESH: Lyssavirus; [SDV]Life Sciences [q-bio]; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; Pipistrellus pipistrellus
• Online Access: https://hal-pasteur.archives-ouvertes.fr/pasteur-01430072; https://hal-pasteur.archives-ouvertes.fr/pasteur-01430072/document; https://hal-pasteur.archives-ouvertes.fr/pasteur-01430072/file/Lopez-Roig_MultispeciesBatColony_Viruses14.pdf; https://doi.org/10.3390/v6093386

International audience We report an active surveillance study of the occurrence of specific antibodies to European Bat Lyssavirus Type 1 (EBLV-1) in bat species, scarcely studied hitherto, that share the same refuge. From 2004 to 2012, 406 sera were obtained from nine bat species. Blood samples were subjected to a modified fluorescent antibody virus neutralization test to determine the antibody titer. EBLV-1-neutralizing antibodies were detected in six of the nine species analyzed (Pipistrellus pipistrellus, P. kuhlii, Hypsugo savii, Plecotus austriacus, Eptesicus serotinus and Tadarida teniotis). Among all bats sampled, female seroprevalence (20.21%, 95% CI: 14.78%-26.57%) was not significantly higher than the seroprevalence in males (15.02%, 95% CI: 10.51%-20.54%). The results showed that the inter-annual variation in the number of seropositive bats in T. teniotis and P. austriacus showed a peak in 2007 (>70% of EBLV-1 prevalence). However, significant differences were observed in the temporal patterns of the seroprevalence modeling of T. teniotis and P. austriacus. The behavioral ecology of these species involved could explain the different annual fluctuations in EBLV-1 seroprevalence.