Phagocytosis in pup and adult harbour, grey and harp seals.
International audience Knowledge on pinniped immunology is still in its infancy. For instance, age-related and developmental aspects of the immune system in pinnipeds need to be better described. The present study examined the phagocytic activity and efficiency of harbour, grey and harp seal leukocy...
Published in: | Veterinary Immunology and Immunopathology |
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Format: | Article in Journal/Newspaper |
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Online Access: | https://hal-riip.archives-ouvertes.fr/pasteur-00819580 https://doi.org/10.1016/j.vetimm.2009.08.017 |
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ftccsdartic:oai:HAL:pasteur-00819580v1 2023-05-15T16:33:44+02:00 Phagocytosis in pup and adult harbour, grey and harp seals. Frouin, Héloïse Lebeuf, Michel Hammill, Mike Fournier, Michel Institut Armand Frappier (INRS-IAF) Institut National de la Recherche Scientifique Québec (INRS)-Réseau International des Instituts Pasteur (RIIP) Fisheries and Oceans Canada Maurice Lamontagne Institute This work is part of the Research Programme undertaken by the Canada Research Chair in Environmental Immunotoxicology (M.F.). This research project was funded in part by the Department of Fisheries and Oceans (M.L. and M.H.). 2010-04-15 https://hal-riip.archives-ouvertes.fr/pasteur-00819580 https://doi.org/10.1016/j.vetimm.2009.08.017 en eng HAL CCSD Elsevier info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetimm.2009.08.017 info:eu-repo/semantics/altIdentifier/pmid/19766324 pasteur-00819580 https://hal-riip.archives-ouvertes.fr/pasteur-00819580 doi:10.1016/j.vetimm.2009.08.017 PUBMED: 19766324 ISSN: 0165-2427 Veterinary Immunology and Immunopathology https://hal-riip.archives-ouvertes.fr/pasteur-00819580 Veterinary Immunology and Immunopathology, Elsevier, 2010, 134 (3-4), pp.160-8. ⟨10.1016/j.vetimm.2009.08.017⟩ Phagocytosis Harbour seals Grey seals Harp seals Lactation MESH: Animals MESH: Species Specificity MESH: Aging Newborn MESH: Female MESH: Lactation MESH: Leukocytes MESH: Male MESH: Phagocytosis MESH: Phoca MESH: Seals Earless [SDV.TOX]Life Sciences [q-bio]/Toxicology info:eu-repo/semantics/article Journal articles 2010 ftccsdartic https://doi.org/10.1016/j.vetimm.2009.08.017 2020-12-26T03:04:03Z International audience Knowledge on pinniped immunology is still in its infancy. For instance, age-related and developmental aspects of the immune system in pinnipeds need to be better described. The present study examined the phagocytic activity and efficiency of harbour, grey and harp seal leukocytes. In the first part of the study, peripheral blood was collected from captive female harbour seals of various ages. Data showed an age-related decrease in phagocytosis in female harbour seals from sub-adult to adulthood. In the second part of the study, changes in phagocytosis were quantified during lactation in wild newborn harbour, grey and harp seals and in their mothers (harp and grey seals). In newborns of the same age, leukocytes of harbour and harp seals phagocytosed less than those of grey seal pups. The phagocytic activity and efficiency increased significantly from early to mid-lactation in newborn harbour seals, and from early to late lactation in newborn grey seals, which could suggest that the transfer of phagocytosis-promoting factor(s) in colostrum is an important feature of temporary protection for pups. In contrast, no changes in phagocytic activity and efficiency were observed in lactating females of the two seal species, harp and grey, examined. At late lactation, phagocytic activity in both grey and harp seal pups and phagocytic efficiency in grey seal pups were significantly higher than in their mothers. These results could reflect either the capacity of phagocytes of the newborn harp and grey seals to respond to pathogens. Results from this study suggest that the phagocytosis of the seal species examined is not fully developed at birth as it generally increases in pups during lactation. Thereafter, the phagocytic activity of seals appears to decrease throughout adulthood. Article in Journal/Newspaper Harp Seal Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Veterinary Immunology and Immunopathology 134 3-4 160 168 |
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Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
Phagocytosis Harbour seals Grey seals Harp seals Lactation MESH: Animals MESH: Species Specificity MESH: Aging Newborn MESH: Female MESH: Lactation MESH: Leukocytes MESH: Male MESH: Phagocytosis MESH: Phoca MESH: Seals Earless [SDV.TOX]Life Sciences [q-bio]/Toxicology |
spellingShingle |
Phagocytosis Harbour seals Grey seals Harp seals Lactation MESH: Animals MESH: Species Specificity MESH: Aging Newborn MESH: Female MESH: Lactation MESH: Leukocytes MESH: Male MESH: Phagocytosis MESH: Phoca MESH: Seals Earless [SDV.TOX]Life Sciences [q-bio]/Toxicology Frouin, Héloïse Lebeuf, Michel Hammill, Mike Fournier, Michel Phagocytosis in pup and adult harbour, grey and harp seals. |
topic_facet |
Phagocytosis Harbour seals Grey seals Harp seals Lactation MESH: Animals MESH: Species Specificity MESH: Aging Newborn MESH: Female MESH: Lactation MESH: Leukocytes MESH: Male MESH: Phagocytosis MESH: Phoca MESH: Seals Earless [SDV.TOX]Life Sciences [q-bio]/Toxicology |
description |
International audience Knowledge on pinniped immunology is still in its infancy. For instance, age-related and developmental aspects of the immune system in pinnipeds need to be better described. The present study examined the phagocytic activity and efficiency of harbour, grey and harp seal leukocytes. In the first part of the study, peripheral blood was collected from captive female harbour seals of various ages. Data showed an age-related decrease in phagocytosis in female harbour seals from sub-adult to adulthood. In the second part of the study, changes in phagocytosis were quantified during lactation in wild newborn harbour, grey and harp seals and in their mothers (harp and grey seals). In newborns of the same age, leukocytes of harbour and harp seals phagocytosed less than those of grey seal pups. The phagocytic activity and efficiency increased significantly from early to mid-lactation in newborn harbour seals, and from early to late lactation in newborn grey seals, which could suggest that the transfer of phagocytosis-promoting factor(s) in colostrum is an important feature of temporary protection for pups. In contrast, no changes in phagocytic activity and efficiency were observed in lactating females of the two seal species, harp and grey, examined. At late lactation, phagocytic activity in both grey and harp seal pups and phagocytic efficiency in grey seal pups were significantly higher than in their mothers. These results could reflect either the capacity of phagocytes of the newborn harp and grey seals to respond to pathogens. Results from this study suggest that the phagocytosis of the seal species examined is not fully developed at birth as it generally increases in pups during lactation. Thereafter, the phagocytic activity of seals appears to decrease throughout adulthood. |
author2 |
Institut Armand Frappier (INRS-IAF) Institut National de la Recherche Scientifique Québec (INRS)-Réseau International des Instituts Pasteur (RIIP) Fisheries and Oceans Canada Maurice Lamontagne Institute This work is part of the Research Programme undertaken by the Canada Research Chair in Environmental Immunotoxicology (M.F.). This research project was funded in part by the Department of Fisheries and Oceans (M.L. and M.H.). |
format |
Article in Journal/Newspaper |
author |
Frouin, Héloïse Lebeuf, Michel Hammill, Mike Fournier, Michel |
author_facet |
Frouin, Héloïse Lebeuf, Michel Hammill, Mike Fournier, Michel |
author_sort |
Frouin, Héloïse |
title |
Phagocytosis in pup and adult harbour, grey and harp seals. |
title_short |
Phagocytosis in pup and adult harbour, grey and harp seals. |
title_full |
Phagocytosis in pup and adult harbour, grey and harp seals. |
title_fullStr |
Phagocytosis in pup and adult harbour, grey and harp seals. |
title_full_unstemmed |
Phagocytosis in pup and adult harbour, grey and harp seals. |
title_sort |
phagocytosis in pup and adult harbour, grey and harp seals. |
publisher |
HAL CCSD |
publishDate |
2010 |
url |
https://hal-riip.archives-ouvertes.fr/pasteur-00819580 https://doi.org/10.1016/j.vetimm.2009.08.017 |
genre |
Harp Seal |
genre_facet |
Harp Seal |
op_source |
ISSN: 0165-2427 Veterinary Immunology and Immunopathology https://hal-riip.archives-ouvertes.fr/pasteur-00819580 Veterinary Immunology and Immunopathology, Elsevier, 2010, 134 (3-4), pp.160-8. ⟨10.1016/j.vetimm.2009.08.017⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetimm.2009.08.017 info:eu-repo/semantics/altIdentifier/pmid/19766324 pasteur-00819580 https://hal-riip.archives-ouvertes.fr/pasteur-00819580 doi:10.1016/j.vetimm.2009.08.017 PUBMED: 19766324 |
op_doi |
https://doi.org/10.1016/j.vetimm.2009.08.017 |
container_title |
Veterinary Immunology and Immunopathology |
container_volume |
134 |
container_issue |
3-4 |
container_start_page |
160 |
op_container_end_page |
168 |
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1766023430067453952 |