Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features
International audience During the past decade, the kisspeptin system has been identified in various vertebrates,leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors(Kissr).The investigation of recently published genomes from species of phylogenetic interest,such as...
Published in: | Frontiers in Endocrinology |
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Main Authors: | , , , , , |
Other Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
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HAL CCSD
2012
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Online Access: | https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/document https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/file/fendo-03-00173.pdf https://doi.org/10.3389/fendo.2012.00173 |
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ftccsdartic:oai:HAL:mnhn-02861074v1 |
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Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
kisspeptin kisspeptin receptor phylogeny synteny evolutionary history spotted gar coelacanth European eel [SDV]Life Sciences [q-bio] |
spellingShingle |
kisspeptin kisspeptin receptor phylogeny synteny evolutionary history spotted gar coelacanth European eel [SDV]Life Sciences [q-bio] Pasquier, Jérémy Lafont, Anne-Gaëlle Tostivint, Hervé Vaudry, Hubert Rousseau, Karine Dufour, Sylvie Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
topic_facet |
kisspeptin kisspeptin receptor phylogeny synteny evolutionary history spotted gar coelacanth European eel [SDV]Life Sciences [q-bio] |
description |
International audience During the past decade, the kisspeptin system has been identified in various vertebrates,leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors(Kissr).The investigation of recently published genomes from species of phylogenetic interest,such as a chondrichthyan, the elephant shark, an early sarcopterygian, the coelacanth, anon-teleost actinopterygian, the spotted gar, and an early teleost, the European eel, allowedus to get new insights into the molecular diversity and evolution of both Kiss and Kissrfamilies.We identified four Kissr in the spotted gar and coelacanth genomes, providing thefirst evidence of four Kissr genes in vertebrates. We also found three Kiss in the coelacanthand elephant shark genomes revealing two new species, in addition to Xenopus,presenting three Kiss genes. Considering the increasing diversity of kisspeptin system,phylogenetic, and synteny analyses enabled us to clarify both Kiss and Kissr classifications.We also could trace back the evolution of both gene families from the early steps ofvertebrate history. Four Kissr and four Kiss paralogs may have arisen via the two wholegenome duplication rounds (1R and 2R) in early vertebrates.Thiswould have been followedby multiple independent Kiss and Kissr gene losses in the sarcopterygian and actinopterygianlineages. In particular, no impact of the teleost-specific 3R could be recorded on thenumbers of teleost Kissr or Kiss paralogs. The origin of their diversity via 1R and 2R, aswell as the subsequent occurrence of multiple gene losses, represent common featuresof the evolutionary histories of Kiss and Kissr families in vertebrates. In contrast, comparisonsalso revealed un-matching numbers of Kiss and Kissr genes in some species, aswell as a large variability of Kiss/Kissr couples according to species. These discrepanciessupport independent features of the Kiss and Kissr evolutionary histories across vertebrateradiation. |
author2 |
Biologie des Organismes et Ecosystèmes Aquatiques (BOREA) Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)-Muséum national d'Histoire naturelle (MNHN)-Institut de Recherche pour le Développement (IRD)-Sorbonne Université (SU)-Université de Caen Normandie (UNICAEN) Normandie Université (NU)-Normandie Université (NU) Neuroendocrinologie cellulaire et moléculaire Université de Rouen Normandie (UNIROUEN) Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM) Différenciation et communication neuronale et neuroendocrine (DC2N) |
format |
Article in Journal/Newspaper |
author |
Pasquier, Jérémy Lafont, Anne-Gaëlle Tostivint, Hervé Vaudry, Hubert Rousseau, Karine Dufour, Sylvie |
author_facet |
Pasquier, Jérémy Lafont, Anne-Gaëlle Tostivint, Hervé Vaudry, Hubert Rousseau, Karine Dufour, Sylvie |
author_sort |
Pasquier, Jérémy |
title |
Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
title_short |
Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
title_full |
Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
title_fullStr |
Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
title_full_unstemmed |
Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features |
title_sort |
comparative evolutionary histories of kisspeptins and kisspeptin receptors in vertebrates reveal both parallel and divergent features |
publisher |
HAL CCSD |
publishDate |
2012 |
url |
https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/document https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/file/fendo-03-00173.pdf https://doi.org/10.3389/fendo.2012.00173 |
long_lat |
ENVELOPE(162.014,162.014,57.140,57.140) |
geographic |
Gar’ |
geographic_facet |
Gar’ |
genre |
European eel |
genre_facet |
European eel |
op_source |
ISSN: 1664-2392 Frontiers in Endocrinology https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 Frontiers in Endocrinology, Frontiers, 2012, 3, ⟨10.3389/fendo.2012.00173⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.3389/fendo.2012.00173 mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/document https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/file/fendo-03-00173.pdf doi:10.3389/fendo.2012.00173 |
op_rights |
http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.3389/fendo.2012.00173 |
container_title |
Frontiers in Endocrinology |
container_volume |
3 |
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1766404664488624128 |
spelling |
ftccsdartic:oai:HAL:mnhn-02861074v1 2023-05-15T16:08:38+02:00 Comparative Evolutionary Histories of Kisspeptins and Kisspeptin Receptors in Vertebrates Reveal Both Parallel and Divergent Features Pasquier, Jérémy Lafont, Anne-Gaëlle Tostivint, Hervé Vaudry, Hubert Rousseau, Karine Dufour, Sylvie Biologie des Organismes et Ecosystèmes Aquatiques (BOREA) Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)-Muséum national d'Histoire naturelle (MNHN)-Institut de Recherche pour le Développement (IRD)-Sorbonne Université (SU)-Université de Caen Normandie (UNICAEN) Normandie Université (NU)-Normandie Université (NU) Neuroendocrinologie cellulaire et moléculaire Université de Rouen Normandie (UNIROUEN) Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM) Différenciation et communication neuronale et neuroendocrine (DC2N) 2012 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/document https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/file/fendo-03-00173.pdf https://doi.org/10.3389/fendo.2012.00173 en eng HAL CCSD Frontiers info:eu-repo/semantics/altIdentifier/doi/10.3389/fendo.2012.00173 mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/document https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074/file/fendo-03-00173.pdf doi:10.3389/fendo.2012.00173 http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess ISSN: 1664-2392 Frontiers in Endocrinology https://hal-mnhn.archives-ouvertes.fr/mnhn-02861074 Frontiers in Endocrinology, Frontiers, 2012, 3, ⟨10.3389/fendo.2012.00173⟩ kisspeptin kisspeptin receptor phylogeny synteny evolutionary history spotted gar coelacanth European eel [SDV]Life Sciences [q-bio] info:eu-repo/semantics/article Journal articles 2012 ftccsdartic https://doi.org/10.3389/fendo.2012.00173 2021-12-19T00:09:05Z International audience During the past decade, the kisspeptin system has been identified in various vertebrates,leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors(Kissr).The investigation of recently published genomes from species of phylogenetic interest,such as a chondrichthyan, the elephant shark, an early sarcopterygian, the coelacanth, anon-teleost actinopterygian, the spotted gar, and an early teleost, the European eel, allowedus to get new insights into the molecular diversity and evolution of both Kiss and Kissrfamilies.We identified four Kissr in the spotted gar and coelacanth genomes, providing thefirst evidence of four Kissr genes in vertebrates. We also found three Kiss in the coelacanthand elephant shark genomes revealing two new species, in addition to Xenopus,presenting three Kiss genes. Considering the increasing diversity of kisspeptin system,phylogenetic, and synteny analyses enabled us to clarify both Kiss and Kissr classifications.We also could trace back the evolution of both gene families from the early steps ofvertebrate history. Four Kissr and four Kiss paralogs may have arisen via the two wholegenome duplication rounds (1R and 2R) in early vertebrates.Thiswould have been followedby multiple independent Kiss and Kissr gene losses in the sarcopterygian and actinopterygianlineages. In particular, no impact of the teleost-specific 3R could be recorded on thenumbers of teleost Kissr or Kiss paralogs. The origin of their diversity via 1R and 2R, aswell as the subsequent occurrence of multiple gene losses, represent common featuresof the evolutionary histories of Kiss and Kissr families in vertebrates. In contrast, comparisonsalso revealed un-matching numbers of Kiss and Kissr genes in some species, aswell as a large variability of Kiss/Kissr couples according to species. These discrepanciessupport independent features of the Kiss and Kissr evolutionary histories across vertebrateradiation. Article in Journal/Newspaper European eel Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Gar’ ENVELOPE(162.014,162.014,57.140,57.140) Frontiers in Endocrinology 3 |