The ancient Yakuts: a population genetic enigma
International audience This study is part of an ongoing project aiming at determining the ethnogenesis of an eastern Siberian ethnic group, the Yakuts, on the basis of archaeological excavations carried out over a period of 10 years in three regions of Yakutia: Central Yakutia, the Vilyuy River basi...
Published in: | Philosophical Transactions of the Royal Society B: Biological Sciences |
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Main Authors: | , , , , , , , , |
Other Authors: | , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2015
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Subjects: | |
Online Access: | https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/document https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/file/Keyser-etal-PhTRSocB-abstract.pdf https://doi.org/10.1098/rstb.2013.0385 |
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ftccsdartic:oai:HAL:lirmm-01170676v1 |
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Open Polar |
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Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
Yakuts Short tandem repeats Ancient DNA Kinship geneticsmolecular biology [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM] |
spellingShingle |
Yakuts Short tandem repeats Ancient DNA Kinship geneticsmolecular biology [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM] Keyser, Christine Hollard, Clemence Gonzalez, Angela Fausser, Jean-Luc Rivals, Eric Alexeev, Anatoly Nikolayevich Riberon, Alexandre Crubezy, Eric Ludes, Bertrand The ancient Yakuts: a population genetic enigma |
topic_facet |
Yakuts Short tandem repeats Ancient DNA Kinship geneticsmolecular biology [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM] |
description |
International audience This study is part of an ongoing project aiming at determining the ethnogenesis of an eastern Siberian ethnic group, the Yakuts, on the basis of archaeological excavations carried out over a period of 10 years in three regions of Yakutia: Central Yakutia, the Vilyuy River basin and the Verkhoyansk area. In this study, genetic analyses were carried out on skeletal remains from 130 individuals of unknown ancestry dated mainly from the fifteenth to the nineteenth century AD. Kinship studies were conducted using sets of commercially available autosomal and Y-chromosomal short tandem repeats (STRs) along with hypervariable region I sequences of the mitochondrial DNA. An unexpected and intriguing finding of this work was that the uniparental marker systems did not always corroborate results from autosomal DNA analyses; in some cases, false-positive relationships were observed. These discrepancies revealed that 15 autosomal STR loci are not sufficient to discriminate between first degree relatives and more distantly related individuals in our ancient Yakut sample. The Y-STR analyses led to similar conclusions, because the current Y-STR panels provided the limited resolution of the paternal lineages. |
author2 |
Anthropologie Moléculaire et Imagerie de Synthèse (AMIS) Université Toulouse III - Paul Sabatier (UT3) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS) Méthodes et Algorithmes pour la Bioinformatique (MAB) Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM) Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) Institut de Biologie Computationnelle (IBC) Institut National de la Recherche Agronomique (INRA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS) Medical Institute Yakutsk Evolution et Diversité Biologique (EDB) Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées Institut de Médecine Légale - IML (Paris, France) - Human Adaptation programme of the French Polar Institute Paul Emile Victor- French Archaeological Missions in Oriental Siberia (Ministry of Foreign and European Affairs, France)- North-Eastern Federal University (Yakutsk, Sakha Republic) |
format |
Article in Journal/Newspaper |
author |
Keyser, Christine Hollard, Clemence Gonzalez, Angela Fausser, Jean-Luc Rivals, Eric Alexeev, Anatoly Nikolayevich Riberon, Alexandre Crubezy, Eric Ludes, Bertrand |
author_facet |
Keyser, Christine Hollard, Clemence Gonzalez, Angela Fausser, Jean-Luc Rivals, Eric Alexeev, Anatoly Nikolayevich Riberon, Alexandre Crubezy, Eric Ludes, Bertrand |
author_sort |
Keyser, Christine |
title |
The ancient Yakuts: a population genetic enigma |
title_short |
The ancient Yakuts: a population genetic enigma |
title_full |
The ancient Yakuts: a population genetic enigma |
title_fullStr |
The ancient Yakuts: a population genetic enigma |
title_full_unstemmed |
The ancient Yakuts: a population genetic enigma |
title_sort |
ancient yakuts: a population genetic enigma |
publisher |
HAL CCSD |
publishDate |
2015 |
url |
https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/document https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/file/Keyser-etal-PhTRSocB-abstract.pdf https://doi.org/10.1098/rstb.2013.0385 |
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ENVELOPE(-112.453,-112.453,57.591,57.591) ENVELOPE(133.400,133.400,67.544,67.544) |
geographic |
The ''Y'' Verkhoyansk |
geographic_facet |
The ''Y'' Verkhoyansk |
genre |
Yakutia Yakuts |
genre_facet |
Yakutia Yakuts |
op_source |
ISSN: 0962-8436 EISSN: 1471-2970 Philosophical Transactions of the Royal Society B: Biological Sciences https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2015, Discussion meeting issue ‘Ancient DNA: the first three decades’, 370 (1660), pp.20130385. ⟨10.1098/rstb.2013.0385⟩ http://rstb.royalsocietypublishing.org/content/370/1660/20130385 |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1098/rstb.2013.0385 info:eu-repo/semantics/altIdentifier/pmid/25487336 lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/document https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/file/Keyser-etal-PhTRSocB-abstract.pdf doi:10.1098/rstb.2013.0385 PRODINRA: 312345 WOS: 000346147700013 PUBMED: 25487336 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1098/rstb.2013.0385 |
container_title |
Philosophical Transactions of the Royal Society B: Biological Sciences |
container_volume |
370 |
container_issue |
1660 |
container_start_page |
20130385 |
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spelling |
ftccsdartic:oai:HAL:lirmm-01170676v1 2023-05-15T18:44:54+02:00 The ancient Yakuts: a population genetic enigma Keyser, Christine Hollard, Clemence Gonzalez, Angela Fausser, Jean-Luc Rivals, Eric Alexeev, Anatoly Nikolayevich Riberon, Alexandre Crubezy, Eric Ludes, Bertrand Anthropologie Moléculaire et Imagerie de Synthèse (AMIS) Université Toulouse III - Paul Sabatier (UT3) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS) Méthodes et Algorithmes pour la Bioinformatique (MAB) Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM) Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) Institut de Biologie Computationnelle (IBC) Institut National de la Recherche Agronomique (INRA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS) Medical Institute Yakutsk Evolution et Diversité Biologique (EDB) Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées Institut de Médecine Légale - IML (Paris, France) - Human Adaptation programme of the French Polar Institute Paul Emile Victor- French Archaeological Missions in Oriental Siberia (Ministry of Foreign and European Affairs, France)- North-Eastern Federal University (Yakutsk, Sakha Republic) 2015-01-19 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/document https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/file/Keyser-etal-PhTRSocB-abstract.pdf https://doi.org/10.1098/rstb.2013.0385 en eng HAL CCSD Royal Society, The info:eu-repo/semantics/altIdentifier/doi/10.1098/rstb.2013.0385 info:eu-repo/semantics/altIdentifier/pmid/25487336 lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/document https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676/file/Keyser-etal-PhTRSocB-abstract.pdf doi:10.1098/rstb.2013.0385 PRODINRA: 312345 WOS: 000346147700013 PUBMED: 25487336 info:eu-repo/semantics/OpenAccess ISSN: 0962-8436 EISSN: 1471-2970 Philosophical Transactions of the Royal Society B: Biological Sciences https://hal-lirmm.ccsd.cnrs.fr/lirmm-01170676 Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2015, Discussion meeting issue ‘Ancient DNA: the first three decades’, 370 (1660), pp.20130385. ⟨10.1098/rstb.2013.0385⟩ http://rstb.royalsocietypublishing.org/content/370/1660/20130385 Yakuts Short tandem repeats Ancient DNA Kinship geneticsmolecular biology [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM] info:eu-repo/semantics/article Journal articles 2015 ftccsdartic https://doi.org/10.1098/rstb.2013.0385 2021-10-24T11:51:06Z International audience This study is part of an ongoing project aiming at determining the ethnogenesis of an eastern Siberian ethnic group, the Yakuts, on the basis of archaeological excavations carried out over a period of 10 years in three regions of Yakutia: Central Yakutia, the Vilyuy River basin and the Verkhoyansk area. In this study, genetic analyses were carried out on skeletal remains from 130 individuals of unknown ancestry dated mainly from the fifteenth to the nineteenth century AD. Kinship studies were conducted using sets of commercially available autosomal and Y-chromosomal short tandem repeats (STRs) along with hypervariable region I sequences of the mitochondrial DNA. An unexpected and intriguing finding of this work was that the uniparental marker systems did not always corroborate results from autosomal DNA analyses; in some cases, false-positive relationships were observed. These discrepancies revealed that 15 autosomal STR loci are not sufficient to discriminate between first degree relatives and more distantly related individuals in our ancient Yakut sample. The Y-STR analyses led to similar conclusions, because the current Y-STR panels provided the limited resolution of the paternal lineages. Article in Journal/Newspaper Yakutia Yakuts Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) The ''Y'' ENVELOPE(-112.453,-112.453,57.591,57.591) Verkhoyansk ENVELOPE(133.400,133.400,67.544,67.544) Philosophical Transactions of the Royal Society B: Biological Sciences 370 1660 20130385 |