First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters
BackgroundVariants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the...
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Online Access: | https://hal.science/hal-04202472 https://doi.org/10.1186/s12863-019-0791-3 |
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ftccsdartic:oai:HAL:hal-04202472v1 2023-10-09T21:55:04+02:00 First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris Laboratoire de Génétique et Pathologie des Mollusques Marins (LGPMM) Santé, Génétique et Microbiologie des Mollusques (SGMM) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) 2019-12 https://hal.science/hal-04202472 https://doi.org/10.1186/s12863-019-0791-3 en eng HAL CCSD BioMed Central info:eu-repo/semantics/altIdentifier/doi/10.1186/s12863-019-0791-3 hal-04202472 https://hal.science/hal-04202472 doi:10.1186/s12863-019-0791-3 ISSN: 1471-2156 BMC Genetics https://hal.science/hal-04202472 BMC Genetics, 2019, 20 (1), 96 (9p.). ⟨10.1186/s12863-019-0791-3⟩ [SDV]Life Sciences [q-bio] info:eu-repo/semantics/article Journal articles 2019 ftccsdartic https://doi.org/10.1186/s12863-019-0791-3 2023-09-23T22:54:26Z BackgroundVariants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection.ResultsSignificant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant.ConclusionsFuture breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. Article in Journal/Newspaper Pacific oyster Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Pacific BMC Genetics 20 1 |
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Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
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ftccsdartic |
language |
English |
topic |
[SDV]Life Sciences [q-bio] |
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[SDV]Life Sciences [q-bio] Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
topic_facet |
[SDV]Life Sciences [q-bio] |
description |
BackgroundVariants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection.ResultsSignificant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant.ConclusionsFuture breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. |
author2 |
Laboratoire de Génétique et Pathologie des Mollusques Marins (LGPMM) Santé, Génétique et Microbiologie des Mollusques (SGMM) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) |
format |
Article in Journal/Newspaper |
author |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_facet |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_sort |
Divilov, Konstantin |
title |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_short |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_fullStr |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full_unstemmed |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_sort |
first evaluation of resistance to both a california oshv-1 variant and a french oshv-1 microvariant in pacific oysters |
publisher |
HAL CCSD |
publishDate |
2019 |
url |
https://hal.science/hal-04202472 https://doi.org/10.1186/s12863-019-0791-3 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Pacific oyster |
genre_facet |
Pacific oyster |
op_source |
ISSN: 1471-2156 BMC Genetics https://hal.science/hal-04202472 BMC Genetics, 2019, 20 (1), 96 (9p.). ⟨10.1186/s12863-019-0791-3⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12863-019-0791-3 hal-04202472 https://hal.science/hal-04202472 doi:10.1186/s12863-019-0791-3 |
op_doi |
https://doi.org/10.1186/s12863-019-0791-3 |
container_title |
BMC Genetics |
container_volume |
20 |
container_issue |
1 |
_version_ |
1779318865835065344 |