Seaweeds influence oyster microbiota and disease susceptibility

International audience 1-A growing awareness of role that microbiota can play in mediating the effects of pathogens on hosts has given rise to the concept of the pathobiome. Recently, we demonstrated that the Pacific oyster mortality syndrome affecting Crassostrea gigas oysters is caused by infectio...

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Published in:Journal of Animal Ecology
Main Authors: Dugeny, Elyne, de Lorgeril, Julien, Petton, Bruno, Toulza, Eve, Gueguen, Yannick, Pernet, Fabrice
Other Authors: Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Interactions Hôtes-Pathogènes-Environnements (IHPE), Université de Perpignan Via Domitia (UPVD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), European Project: 678589,H2020,H2020-SFS-2015-2,VIVALDI(2016)
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2022
Subjects:
Online Access:https://hal.science/hal-03609497
https://hal.science/hal-03609497/document
https://hal.science/hal-03609497/file/Dugeny-2022-JAnimEcol-Seaweeds-MANUSCRIT.pdf
https://doi.org/10.1111/1365-2656.13662
id ftccsdartic:oai:HAL:hal-03609497v1
record_format openpolar
institution Open Polar
collection Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe)
op_collection_id ftccsdartic
language English
topic bivalve
disease ecology
epidemiology
macroalgae
microbiome
pathogen
[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
spellingShingle bivalve
disease ecology
epidemiology
macroalgae
microbiome
pathogen
[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
Dugeny, Elyne
de Lorgeril, Julien
Petton, Bruno
Toulza, Eve
Gueguen, Yannick
Pernet, Fabrice
Seaweeds influence oyster microbiota and disease susceptibility
topic_facet bivalve
disease ecology
epidemiology
macroalgae
microbiome
pathogen
[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
description International audience 1-A growing awareness of role that microbiota can play in mediating the effects of pathogens on hosts has given rise to the concept of the pathobiome. Recently, we demonstrated that the Pacific oyster mortality syndrome affecting Crassostrea gigas oysters is caused by infection with the Ostreid herpesvirus type 1 (OsHV-1) followed by infection with multiple bacterial taxa. 2-Here we extend the concept of this pathobiome beyond the host species and its bacterial microbiota by investigating how seaweed living in association with oysters influences their response to the disease. We hypothesized that by their mere presence in the environment, different species of seaweeds can positively or negatively influence the risk of disease in oysters by shaping their bacterial microbiota and their immune response. Although seaweed and oysters do not have direct ecological interactions, they are connected by seawater and likely share microbes. 3-To test our hypothesis, oysters were acclimated with green, brown or red algae for 2 weeks and then challenged with OsHV-1. We monitored host survival and pathogen proliferation and performed bacterial microbiota and transcriptome analyses. 4-We found that seaweeds can alter the bacterial microbiota of the host and its response to the disease. More particularly, green algae belonging to the genus Ulva spp. induced bacterial microbiota dysbiosis in oyster and modification of its transcriptional immune response leading to increased susceptibility to the disease. 5-This work provides a better understanding of a marine disease and highlights the importance of considering both macrobiotic and microbiotic interactions for conservation, management and exploitation of marine ecosystems and resources.
author2 Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR)
Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM)
Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
Interactions Hôtes-Pathogènes-Environnements (IHPE)
Université de Perpignan Via Domitia (UPVD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)
European Project: 678589,H2020,H2020-SFS-2015-2,VIVALDI(2016)
format Article in Journal/Newspaper
author Dugeny, Elyne
de Lorgeril, Julien
Petton, Bruno
Toulza, Eve
Gueguen, Yannick
Pernet, Fabrice
author_facet Dugeny, Elyne
de Lorgeril, Julien
Petton, Bruno
Toulza, Eve
Gueguen, Yannick
Pernet, Fabrice
author_sort Dugeny, Elyne
title Seaweeds influence oyster microbiota and disease susceptibility
title_short Seaweeds influence oyster microbiota and disease susceptibility
title_full Seaweeds influence oyster microbiota and disease susceptibility
title_fullStr Seaweeds influence oyster microbiota and disease susceptibility
title_full_unstemmed Seaweeds influence oyster microbiota and disease susceptibility
title_sort seaweeds influence oyster microbiota and disease susceptibility
publisher HAL CCSD
publishDate 2022
url https://hal.science/hal-03609497
https://hal.science/hal-03609497/document
https://hal.science/hal-03609497/file/Dugeny-2022-JAnimEcol-Seaweeds-MANUSCRIT.pdf
https://doi.org/10.1111/1365-2656.13662
geographic Pacific
geographic_facet Pacific
genre Crassostrea gigas
Pacific oyster
genre_facet Crassostrea gigas
Pacific oyster
op_source ISSN: 0021-8790
EISSN: 1365-2656
Journal of Animal Ecology
https://hal.science/hal-03609497
Journal of Animal Ecology, 2022, 91 (4), pp.805-818. ⟨10.1111/1365-2656.13662⟩
https://besjournals.onlinelibrary.wiley.com/doi/abs/10.1111/1365-2656.13662
op_relation info:eu-repo/semantics/altIdentifier/doi/10.1111/1365-2656.13662
info:eu-repo/grantAgreement//678589/EU/Preventing and mitigating farmed bivalve diseases/VIVALDI
hal-03609497
https://hal.science/hal-03609497
https://hal.science/hal-03609497/document
https://hal.science/hal-03609497/file/Dugeny-2022-JAnimEcol-Seaweeds-MANUSCRIT.pdf
doi:10.1111/1365-2656.13662
op_rights info:eu-repo/semantics/OpenAccess
op_doi https://doi.org/10.1111/1365-2656.13662
container_title Journal of Animal Ecology
container_volume 91
container_issue 4
container_start_page 805
op_container_end_page 818
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spelling ftccsdartic:oai:HAL:hal-03609497v1 2024-02-27T08:39:54+00:00 Seaweeds influence oyster microbiota and disease susceptibility Dugeny, Elyne de Lorgeril, Julien Petton, Bruno Toulza, Eve Gueguen, Yannick Pernet, Fabrice Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR) Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM) Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Interactions Hôtes-Pathogènes-Environnements (IHPE) Université de Perpignan Via Domitia (UPVD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) European Project: 678589,H2020,H2020-SFS-2015-2,VIVALDI(2016) 2022 https://hal.science/hal-03609497 https://hal.science/hal-03609497/document https://hal.science/hal-03609497/file/Dugeny-2022-JAnimEcol-Seaweeds-MANUSCRIT.pdf https://doi.org/10.1111/1365-2656.13662 en eng HAL CCSD Wiley info:eu-repo/semantics/altIdentifier/doi/10.1111/1365-2656.13662 info:eu-repo/grantAgreement//678589/EU/Preventing and mitigating farmed bivalve diseases/VIVALDI hal-03609497 https://hal.science/hal-03609497 https://hal.science/hal-03609497/document https://hal.science/hal-03609497/file/Dugeny-2022-JAnimEcol-Seaweeds-MANUSCRIT.pdf doi:10.1111/1365-2656.13662 info:eu-repo/semantics/OpenAccess ISSN: 0021-8790 EISSN: 1365-2656 Journal of Animal Ecology https://hal.science/hal-03609497 Journal of Animal Ecology, 2022, 91 (4), pp.805-818. ⟨10.1111/1365-2656.13662⟩ https://besjournals.onlinelibrary.wiley.com/doi/abs/10.1111/1365-2656.13662 bivalve disease ecology epidemiology macroalgae microbiome pathogen [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] info:eu-repo/semantics/article Journal articles 2022 ftccsdartic https://doi.org/10.1111/1365-2656.13662 2024-01-28T01:26:47Z International audience 1-A growing awareness of role that microbiota can play in mediating the effects of pathogens on hosts has given rise to the concept of the pathobiome. Recently, we demonstrated that the Pacific oyster mortality syndrome affecting Crassostrea gigas oysters is caused by infection with the Ostreid herpesvirus type 1 (OsHV-1) followed by infection with multiple bacterial taxa. 2-Here we extend the concept of this pathobiome beyond the host species and its bacterial microbiota by investigating how seaweed living in association with oysters influences their response to the disease. We hypothesized that by their mere presence in the environment, different species of seaweeds can positively or negatively influence the risk of disease in oysters by shaping their bacterial microbiota and their immune response. Although seaweed and oysters do not have direct ecological interactions, they are connected by seawater and likely share microbes. 3-To test our hypothesis, oysters were acclimated with green, brown or red algae for 2 weeks and then challenged with OsHV-1. We monitored host survival and pathogen proliferation and performed bacterial microbiota and transcriptome analyses. 4-We found that seaweeds can alter the bacterial microbiota of the host and its response to the disease. More particularly, green algae belonging to the genus Ulva spp. induced bacterial microbiota dysbiosis in oyster and modification of its transcriptional immune response leading to increased susceptibility to the disease. 5-This work provides a better understanding of a marine disease and highlights the importance of considering both macrobiotic and microbiotic interactions for conservation, management and exploitation of marine ecosystems and resources. Article in Journal/Newspaper Crassostrea gigas Pacific oyster Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Pacific Journal of Animal Ecology 91 4 805 818