PAH metabolites in fish bile: From the Seine estuary to Iceland

• Published in: Marine Environmental Research
• Main Authors: Kammann, U., Akcha, F., Budzinski, H., Burgeot, T., Gubbins, M.J., Lang, T., Le Menach, K., Vethaak, A.D., Hylland, K.
• Other Authors: Thünen Institut of Fisheries Ecology, Palmaille 9, D-22767, Hamburg & Deichstr. 12, 27472 Cuxhaven, Germany, Ifremer, Department of Biogeochemistry and Ecotoxicology, BP 21105, 44311 Nantes Cedex 03, France, Institut des Sciences Moléculaires (ISM), Université Montesquieu - Bordeaux 4-Université Sciences et Technologies - Bordeaux 1-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), FRS Marine Laboratory, 375 Victoria Road, Aberdeen, AB11 9DB Scotland, UK, Institute for Environmental Studies (IVM), VU University Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, The Netherlands, Department of Biology, University of Oslo, Pb 1066, Blindern, N-0316 Oslo, Norway, Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, N-0349 Oslo, Norway
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2017
• Subjects: GEOF; [SDE]Environmental Sciences; Iceland
• Online Access: https://hal.archives-ouvertes.fr/hal-03157580; https://doi.org/10.1016/j.marenvres.2016.02.014

International audience Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. The International Workshop on Integrated Assessment of Contaminant Impacts on the North Sea (ICON) provided the framework to investigate biomarker responses as well as contaminant concentrations side by side in marine ecosystems. Concentrations of the main PAH metabolites 1-hydroxypyrene, 1-hydroxyphenanthren and 3-hydroxybenzo(a)pyrene were determined in bile by HPLC with fluorescence detection. Fish species under investigation were dab (Limanda limanda), flounder (Platichthys flesus) and haddock (Melanogrammus aeglefinus). A contamination gradient was demonstrated from the low contaminated waters of Iceland and off-shore regions of the North Sea towards higher concentrations in coastal areas. Concentrations of PAH metabolites differed primarily according to sampling region and secondarily to species.