Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate)
© 2016 American Chemical Society. The enzyme-catalyzed synthesis of fully biobased poly(3-hydroxybutyrate-co-butylene succinate) (poly(HB-co-BS)) copolyesters is reported for the first time. Different Candida antarctica lipase B (CALB)-catalyzed copolyesters were produced in solution, via a one-step...
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ftccsdartic:oai:HAL:hal-03114433v1 2023-05-15T13:47:30+02:00 Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) Debuissy, Thibaud Pollet, Eric Avérous, Luc Institut de chimie et procédés pour l'énergie, l'environnement et la santé (ICPEES) Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) 2016 https://hal.archives-ouvertes.fr/hal-03114433 https://doi.org/10.1021/acs.biomac.6b01494 en eng HAL CCSD info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.biomac.6b01494 hal-03114433 https://hal.archives-ouvertes.fr/hal-03114433 doi:10.1021/acs.biomac.6b01494 Biomacromolecules https://hal.archives-ouvertes.fr/hal-03114433 Biomacromolecules, 2016, 17 (12), ⟨10.1021/acs.biomac.6b01494⟩ [CHIM.POLY]Chemical Sciences/Polymers info:eu-repo/semantics/article Journal articles 2016 ftccsdartic https://doi.org/10.1021/acs.biomac.6b01494 2021-12-12T00:50:38Z © 2016 American Chemical Society. The enzyme-catalyzed synthesis of fully biobased poly(3-hydroxybutyrate-co-butylene succinate) (poly(HB-co-BS)) copolyesters is reported for the first time. Different Candida antarctica lipase B (CALB)-catalyzed copolyesters were produced in solution, via a one-step or a two-step process from 1,4-butanediol, diethyl succinate, and synthesized telechelic hydroxylated poly(3-hydroxybutyrate) oligomers (PHB-diol). The influence of the ester/hydroxyl functionality ratio, catalyst amount, PHB-diol oligomer chain length, hydroxybutyrate (HB) and butylene succinate (BS) contents, and the nature of the solvent were investigated. The two-step process allowed the synthesis of copolyesters of high molar masses (M n up to 18 000 g/mol), compared to the one-step process (M n ∼ 8000 g/mol), without thermal degradation. The highest molar masses were obtained with diphenyl ether as solvent, compared with dibenzyl ether or anisole. During the two-step process, the transesterification rate between the HB and BS segments (i) increased with increasing amount of catalyst and decreasing molar mass of the PHB-diol oligomer, (ii) decreased when anisole was used as the solvent, and (iii) was not influenced by the HB/BS ratio. Tendencies toward block or random macromolecular architectures were observed as a function of the reaction time, the PHB-diol oligomer chain length, and the chosen solvent. Immobilized CALB-catalyzed copolyesters were thermally stable up to 200 °C. The crystalline structure of the poly(HB-co-BS) copolyesters depended on the HB/BS ratio and the average sequence length of the segments. The crystalline content, T m and T c decreased with increasing HB content and the randomness of the copolymer structure. Article in Journal/Newspaper Antarc* Antarctica Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Biomacromolecules 17 12 4054 4063 |
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Open Polar |
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Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
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ftccsdartic |
language |
English |
topic |
[CHIM.POLY]Chemical Sciences/Polymers |
spellingShingle |
[CHIM.POLY]Chemical Sciences/Polymers Debuissy, Thibaud Pollet, Eric Avérous, Luc Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
topic_facet |
[CHIM.POLY]Chemical Sciences/Polymers |
description |
© 2016 American Chemical Society. The enzyme-catalyzed synthesis of fully biobased poly(3-hydroxybutyrate-co-butylene succinate) (poly(HB-co-BS)) copolyesters is reported for the first time. Different Candida antarctica lipase B (CALB)-catalyzed copolyesters were produced in solution, via a one-step or a two-step process from 1,4-butanediol, diethyl succinate, and synthesized telechelic hydroxylated poly(3-hydroxybutyrate) oligomers (PHB-diol). The influence of the ester/hydroxyl functionality ratio, catalyst amount, PHB-diol oligomer chain length, hydroxybutyrate (HB) and butylene succinate (BS) contents, and the nature of the solvent were investigated. The two-step process allowed the synthesis of copolyesters of high molar masses (M n up to 18 000 g/mol), compared to the one-step process (M n ∼ 8000 g/mol), without thermal degradation. The highest molar masses were obtained with diphenyl ether as solvent, compared with dibenzyl ether or anisole. During the two-step process, the transesterification rate between the HB and BS segments (i) increased with increasing amount of catalyst and decreasing molar mass of the PHB-diol oligomer, (ii) decreased when anisole was used as the solvent, and (iii) was not influenced by the HB/BS ratio. Tendencies toward block or random macromolecular architectures were observed as a function of the reaction time, the PHB-diol oligomer chain length, and the chosen solvent. Immobilized CALB-catalyzed copolyesters were thermally stable up to 200 °C. The crystalline structure of the poly(HB-co-BS) copolyesters depended on the HB/BS ratio and the average sequence length of the segments. The crystalline content, T m and T c decreased with increasing HB content and the randomness of the copolymer structure. |
author2 |
Institut de chimie et procédés pour l'énergie, l'environnement et la santé (ICPEES) Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) |
format |
Article in Journal/Newspaper |
author |
Debuissy, Thibaud Pollet, Eric Avérous, Luc |
author_facet |
Debuissy, Thibaud Pollet, Eric Avérous, Luc |
author_sort |
Debuissy, Thibaud |
title |
Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
title_short |
Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
title_full |
Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
title_fullStr |
Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
title_full_unstemmed |
Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate) |
title_sort |
enzymatic synthesis of a bio-based copolyester from poly(butylene succinate) and poly((r)-3-hydroxybutyrate) |
publisher |
HAL CCSD |
publishDate |
2016 |
url |
https://hal.archives-ouvertes.fr/hal-03114433 https://doi.org/10.1021/acs.biomac.6b01494 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Biomacromolecules https://hal.archives-ouvertes.fr/hal-03114433 Biomacromolecules, 2016, 17 (12), ⟨10.1021/acs.biomac.6b01494⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.biomac.6b01494 hal-03114433 https://hal.archives-ouvertes.fr/hal-03114433 doi:10.1021/acs.biomac.6b01494 |
op_doi |
https://doi.org/10.1021/acs.biomac.6b01494 |
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Biomacromolecules |
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17 |
container_issue |
12 |
container_start_page |
4054 |
op_container_end_page |
4063 |
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1766247239004454912 |