Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids
© 2015 Elsevier B.V.Lipase-based catalysts were tested for the ring-opening polymerization of d-, l- and d,l-lactide isomers, highlighting the different specificity of the enzyme toward these isomers. Free form of Candida antarctica lipase B (CALB) and its clay- and acrylic resin- immobilized forms...
Published in: | Journal of Molecular Catalysis B: Enzymatic |
---|---|
Main Authors: | , , , , , |
Other Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2015
|
Subjects: | |
Online Access: | https://hal.archives-ouvertes.fr/hal-03112160 https://doi.org/10.1016/j.molcatb.2015.01.011 |
id |
ftccsdartic:oai:HAL:hal-03112160v1 |
---|---|
record_format |
openpolar |
institution |
Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
[CHIM.POLY]Chemical Sciences/Polymers |
spellingShingle |
[CHIM.POLY]Chemical Sciences/Polymers Düşkünkorur, H Bégué, A Pollet, Eric Phalip, Vincent Güvenilir, Y Avérous, Luc Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
topic_facet |
[CHIM.POLY]Chemical Sciences/Polymers |
description |
© 2015 Elsevier B.V.Lipase-based catalysts were tested for the ring-opening polymerization of d-, l- and d,l-lactide isomers, highlighting the different specificity of the enzyme toward these isomers. Free form of Candida antarctica lipase B (CALB) and its clay- and acrylic resin- immobilized forms were compared. For l- and d,l-lactide monomers only short oligomers were obtained. The acrylic resin immobilized form of CALB (NOVO-435) led to a complete conversion of d-lactide to PDLA with a Mn of 2600 g/mol, whereas the clay-immobilized and free forms of CALB exhibited slower kinetics and produced chains of lower Mn. Copolymerization reactions between ε-caprolactone and lactide isomers were performed using NOVO-435 as bio-catalyst. Random copolyesters were successfully synthesized by copolymerizing d-lactide with ε-caprolactone. Better results were obtained with a two-step reaction, starting from presynthesized polycaprolactone chains, compared with the one-pot copolymerization. Conducting this two-step copolymerization in the presence of organo-modified montmorillonite allowed the successful synthesis of copolymer/clay nanohybrids. |
author2 |
Laboratoire des Matériaux, Surfaces et Procédés pour la Catalyse (LMSPC) Institut de chimie et procédés pour l'énergie, l'environnement et la santé (ICPEES) Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Biotechnologie et signalisation cellulaire (BSC) Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS) |
format |
Article in Journal/Newspaper |
author |
Düşkünkorur, H Bégué, A Pollet, Eric Phalip, Vincent Güvenilir, Y Avérous, Luc |
author_facet |
Düşkünkorur, H Bégué, A Pollet, Eric Phalip, Vincent Güvenilir, Y Avérous, Luc |
author_sort |
Düşkünkorur, H |
title |
Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
title_short |
Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
title_full |
Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
title_fullStr |
Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
title_full_unstemmed |
Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids |
title_sort |
enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. toward the in situ synthesis of organic/inorganic nanohybrids |
publisher |
HAL CCSD |
publishDate |
2015 |
url |
https://hal.archives-ouvertes.fr/hal-03112160 https://doi.org/10.1016/j.molcatb.2015.01.011 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Journal of Molecular Catalysis B: Enzymatic https://hal.archives-ouvertes.fr/hal-03112160 Journal of Molecular Catalysis B: Enzymatic, 2015, 115, ⟨10.1016/j.molcatb.2015.01.011⟩ ///C:/Users/averous/Documents/Mendeley Desktop/Journal of Molecular Catalysis Enzymatic Halle.pdf |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.molcatb.2015.01.011 hal-03112160 https://hal.archives-ouvertes.fr/hal-03112160 doi:10.1016/j.molcatb.2015.01.011 |
op_doi |
https://doi.org/10.1016/j.molcatb.2015.01.011 |
container_title |
Journal of Molecular Catalysis B: Enzymatic |
container_volume |
115 |
container_start_page |
20 |
op_container_end_page |
28 |
_version_ |
1766247239209975808 |
spelling |
ftccsdartic:oai:HAL:hal-03112160v1 2023-05-15T13:47:30+02:00 Enzymatic ring-opening (co)polymerization of lactide stereoisomers catalyzed by lipases. Toward the in situ synthesis of organic/inorganic nanohybrids Düşkünkorur, H Bégué, A Pollet, Eric Phalip, Vincent Güvenilir, Y Avérous, Luc Laboratoire des Matériaux, Surfaces et Procédés pour la Catalyse (LMSPC) Institut de chimie et procédés pour l'énergie, l'environnement et la santé (ICPEES) Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE) Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Biotechnologie et signalisation cellulaire (BSC) Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS) 2015 https://hal.archives-ouvertes.fr/hal-03112160 https://doi.org/10.1016/j.molcatb.2015.01.011 en eng HAL CCSD info:eu-repo/semantics/altIdentifier/doi/10.1016/j.molcatb.2015.01.011 hal-03112160 https://hal.archives-ouvertes.fr/hal-03112160 doi:10.1016/j.molcatb.2015.01.011 Journal of Molecular Catalysis B: Enzymatic https://hal.archives-ouvertes.fr/hal-03112160 Journal of Molecular Catalysis B: Enzymatic, 2015, 115, ⟨10.1016/j.molcatb.2015.01.011⟩ ///C:/Users/averous/Documents/Mendeley Desktop/Journal of Molecular Catalysis Enzymatic Halle.pdf [CHIM.POLY]Chemical Sciences/Polymers info:eu-repo/semantics/article Journal articles 2015 ftccsdartic https://doi.org/10.1016/j.molcatb.2015.01.011 2021-12-12T00:50:48Z © 2015 Elsevier B.V.Lipase-based catalysts were tested for the ring-opening polymerization of d-, l- and d,l-lactide isomers, highlighting the different specificity of the enzyme toward these isomers. Free form of Candida antarctica lipase B (CALB) and its clay- and acrylic resin- immobilized forms were compared. For l- and d,l-lactide monomers only short oligomers were obtained. The acrylic resin immobilized form of CALB (NOVO-435) led to a complete conversion of d-lactide to PDLA with a Mn of 2600 g/mol, whereas the clay-immobilized and free forms of CALB exhibited slower kinetics and produced chains of lower Mn. Copolymerization reactions between ε-caprolactone and lactide isomers were performed using NOVO-435 as bio-catalyst. Random copolyesters were successfully synthesized by copolymerizing d-lactide with ε-caprolactone. Better results were obtained with a two-step reaction, starting from presynthesized polycaprolactone chains, compared with the one-pot copolymerization. Conducting this two-step copolymerization in the presence of organo-modified montmorillonite allowed the successful synthesis of copolymer/clay nanohybrids. Article in Journal/Newspaper Antarc* Antarctica Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Journal of Molecular Catalysis B: Enzymatic 115 20 28 |