Lipase catalyzed synthesis of biopolyester and related clay-based nanohybrids

• Main Authors: Öztürk, H, Pollet, Eric, Hebraud, Anne, Avérous, Luc
• Other Authors: Laboratoire des Matériaux, Surfaces et Procédés pour la Catalyse (LMSPC), Institut de chimie et procédés pour l'énergie, l'environnement et la santé (ICPEES), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
• Format: Book Part
• Language: English
• Published: HAL CCSD 2011
• Subjects: [CHIM.POLY]Chemical Sciences/Polymers; Antarc*; Antarctica
• Online Access: https://hal.archives-ouvertes.fr/hal-03112151

Biosynthetic pathway, like enzymatic ring opening polymerization (ROP) of lactones, attracts attention as a new trend of biodegradable polymer synthesis due to its non-toxicity, mild reaction requirement and recyclability of immobilized enzyme. Besides the enzyme-catalyzed synthesis of biopolyesters, key researches are conducted nowadays on the elaboration of biocomposites in combination with inorganic (nano)particles. The goal is to improve some of these polyesters properties for specific biomedical applications. In parallel, the use of clays as inorganic porous supports to immobilize enzymes has also been described. This chapter aims at presenting the use and development of original catalytic systems based on lipases which are efficient for polyester synthesis and allowing the preparation of hybrid materials based on clay nanoparticles grafted with such polyesters. For this, ε-caprolactone (ε-CL) polymerization catalyzed by Candida antarctica lipase B (CALB) was carried out in the presence of montmorillonite and sepiolite clays to obtain organic/inorganic nanohybrids through polymer chains grafting and growth from the hydroxyl groups of the clay. Both the free form and immobilized form of CALB have been tested as catalytic systems and their efficiency has been compared. The polymerization kinetics and resulting products were fully characterized with NMR, SEC, DSC and TGA analyses. © 2011 Nova Science Publishers, Inc.