The major outer membrane protein OmpU of Vibrio splendidus contributes to host antimicrobial peptide resistance and is required for virulence in the oyster Crassostrea gigas

International audience Vibrio splendidus, strain LGP32, is an oyster pathogen associated with the summer mortalities affecting the production of Crassostrea gigas oysters worldwide. Vibrio splendidus LGP32 was shown to resist to up to 10 microM Cg-Def defensin and Cg-BPI bactericidal permeability in...

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Published in:Environmental Microbiology
Main Authors: Duperthuy, Marylise, Binesse, Johan, Le Roux, Frédérique, Romestand, Bernard, Caro, Audrey, Got, Patrice, Givaudan, Alain, Mazel, Didier, Bachère, Evelyne, Destoumieux-Garzón, Delphine
Other Authors: Université Montpellier 2 - Sciences et Techniques (UM2), Ecosystèmes lagunaires : organisation biologique et fonctionnement (ECOLAG), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS), Plasticité du Génome Bactérien (PGB), Institut Pasteur Paris -Centre National de la Recherche Scientifique (CNRS), Laboratoire de Génétique et Pathologie (LGP), Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Ecologie microbienne des insectes et interactions hôte-pathogène (EMIP), Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2), This work received financial support from Ifremer and CNRS. It was awarded a “chercheur(se) d'avenir” grant from the Languedoc-Roussillon region.
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2010
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Online Access:https://hal.inrae.fr/hal-02667966
https://doi.org/10.1111/j.1462-2920.2009.02138.x