Genetic effects of fatty acid composition in muscle of Atlantic salmon
International audience AbstractBackgroundThe replacement of fish oil (FO) and fishmeal with plant ingredients in the diet of farmed Atlantic salmon has resulted in reduced levels of the health-promoting long-chain polyunsaturated omega-3 fatty acids (n-3 LC-PUFA) eicosapentaenoic (EPA; 20:5n-3) and...
Published in: | Genetics Selection Evolution |
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ftccsdartic:oai:HAL:hal-02405234v1 2023-05-15T15:30:42+02:00 Genetic effects of fatty acid composition in muscle of Atlantic salmon Horn, Siri S. Ruyter, Bente Meuwissen, Theo H. E. Hillestad, Borghild Sonesson, Anna K. Norwegian University of Life Sciences (NMBU) 2018-12 https://hal.archives-ouvertes.fr/hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234/document https://hal.archives-ouvertes.fr/hal-02405234/file/12711_2018_Article_394.pdf https://doi.org/10.1186/s12711-018-0394-x en eng HAL CCSD BioMed Central info:eu-repo/semantics/altIdentifier/doi/10.1186/s12711-018-0394-x hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234/document https://hal.archives-ouvertes.fr/hal-02405234/file/12711_2018_Article_394.pdf doi:10.1186/s12711-018-0394-x http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess ISSN: 0999-193X EISSN: 1297-9686 Genetics Selection Evolution https://hal.archives-ouvertes.fr/hal-02405234 Genetics Selection Evolution, BioMed Central, 2018, 50 (1), pp.23. ⟨10.1186/s12711-018-0394-x⟩ [SDV]Life Sciences [q-bio] info:eu-repo/semantics/article Journal articles 2018 ftccsdartic https://doi.org/10.1186/s12711-018-0394-x 2021-02-20T23:51:23Z International audience AbstractBackgroundThe replacement of fish oil (FO) and fishmeal with plant ingredients in the diet of farmed Atlantic salmon has resulted in reduced levels of the health-promoting long-chain polyunsaturated omega-3 fatty acids (n-3 LC-PUFA) eicosapentaenoic (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) in their filets. Previous studies showed the potential of selective breeding to increase n-3 LC-PUFA levels in salmon tissues, but knowledge on the genetic parameters for individual muscle fatty acids (FA) and their relationships with other traits is still lacking. Thus, we estimated genetic parameters for muscle content of individual FA, and their relationships with lipid deposition traits, muscle pigmentation, sea lice and pancreas disease in slaughter-sized Atlantic salmon. Our aim was to evaluate the selection potential for increased n-3 LC-PUFA content and provide insight into FA metabolism in Atlantic salmon muscle.ResultsAmong the n-3 PUFA, proportional contents of alpha-linolenic acid (ALA; 18:3n-3) and DHA had the highest heritability (0.26) and EPA the lowest (0.09). Genetic correlations of EPA and DHA proportions with muscle fat differed considerably, 0.60 and 0.01, respectively. The genetic correlation of DHA proportion with visceral fat was positive and high (0.61), whereas that of EPA proportion with lice density was negative. FA that are in close proximity along the bioconversion pathway showed positive correlations with each other, whereas the start (ALA) and end-point (DHA) of the pathway were negatively correlated (− 0.28), indicating active bioconversion of ALA to DHA in the muscle of fish fed high FO-diet.ConclusionsSince contents of individual FA in salmon muscle show additive genetic variation, changing FA composition by selective breeding is possible. Taken together, our results show that the heritabilities of individual n-3 LC-PUFA and their genetic correlations with other traits vary, which indicates that they play different roles in muscle lipid ... Article in Journal/Newspaper Atlantic salmon Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Slaughter ENVELOPE(-85.633,-85.633,-78.617,-78.617) Genetics Selection Evolution 50 1 |
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Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
[SDV]Life Sciences [q-bio] |
spellingShingle |
[SDV]Life Sciences [q-bio] Horn, Siri S. Ruyter, Bente Meuwissen, Theo H. E. Hillestad, Borghild Sonesson, Anna K. Genetic effects of fatty acid composition in muscle of Atlantic salmon |
topic_facet |
[SDV]Life Sciences [q-bio] |
description |
International audience AbstractBackgroundThe replacement of fish oil (FO) and fishmeal with plant ingredients in the diet of farmed Atlantic salmon has resulted in reduced levels of the health-promoting long-chain polyunsaturated omega-3 fatty acids (n-3 LC-PUFA) eicosapentaenoic (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) in their filets. Previous studies showed the potential of selective breeding to increase n-3 LC-PUFA levels in salmon tissues, but knowledge on the genetic parameters for individual muscle fatty acids (FA) and their relationships with other traits is still lacking. Thus, we estimated genetic parameters for muscle content of individual FA, and their relationships with lipid deposition traits, muscle pigmentation, sea lice and pancreas disease in slaughter-sized Atlantic salmon. Our aim was to evaluate the selection potential for increased n-3 LC-PUFA content and provide insight into FA metabolism in Atlantic salmon muscle.ResultsAmong the n-3 PUFA, proportional contents of alpha-linolenic acid (ALA; 18:3n-3) and DHA had the highest heritability (0.26) and EPA the lowest (0.09). Genetic correlations of EPA and DHA proportions with muscle fat differed considerably, 0.60 and 0.01, respectively. The genetic correlation of DHA proportion with visceral fat was positive and high (0.61), whereas that of EPA proportion with lice density was negative. FA that are in close proximity along the bioconversion pathway showed positive correlations with each other, whereas the start (ALA) and end-point (DHA) of the pathway were negatively correlated (− 0.28), indicating active bioconversion of ALA to DHA in the muscle of fish fed high FO-diet.ConclusionsSince contents of individual FA in salmon muscle show additive genetic variation, changing FA composition by selective breeding is possible. Taken together, our results show that the heritabilities of individual n-3 LC-PUFA and their genetic correlations with other traits vary, which indicates that they play different roles in muscle lipid ... |
author2 |
Norwegian University of Life Sciences (NMBU) |
format |
Article in Journal/Newspaper |
author |
Horn, Siri S. Ruyter, Bente Meuwissen, Theo H. E. Hillestad, Borghild Sonesson, Anna K. |
author_facet |
Horn, Siri S. Ruyter, Bente Meuwissen, Theo H. E. Hillestad, Borghild Sonesson, Anna K. |
author_sort |
Horn, Siri S. |
title |
Genetic effects of fatty acid composition in muscle of Atlantic salmon |
title_short |
Genetic effects of fatty acid composition in muscle of Atlantic salmon |
title_full |
Genetic effects of fatty acid composition in muscle of Atlantic salmon |
title_fullStr |
Genetic effects of fatty acid composition in muscle of Atlantic salmon |
title_full_unstemmed |
Genetic effects of fatty acid composition in muscle of Atlantic salmon |
title_sort |
genetic effects of fatty acid composition in muscle of atlantic salmon |
publisher |
HAL CCSD |
publishDate |
2018 |
url |
https://hal.archives-ouvertes.fr/hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234/document https://hal.archives-ouvertes.fr/hal-02405234/file/12711_2018_Article_394.pdf https://doi.org/10.1186/s12711-018-0394-x |
long_lat |
ENVELOPE(-85.633,-85.633,-78.617,-78.617) |
geographic |
Slaughter |
geographic_facet |
Slaughter |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
ISSN: 0999-193X EISSN: 1297-9686 Genetics Selection Evolution https://hal.archives-ouvertes.fr/hal-02405234 Genetics Selection Evolution, BioMed Central, 2018, 50 (1), pp.23. ⟨10.1186/s12711-018-0394-x⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12711-018-0394-x hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234 https://hal.archives-ouvertes.fr/hal-02405234/document https://hal.archives-ouvertes.fr/hal-02405234/file/12711_2018_Article_394.pdf doi:10.1186/s12711-018-0394-x |
op_rights |
http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1186/s12711-018-0394-x |
container_title |
Genetics Selection Evolution |
container_volume |
50 |
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1 |
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