Vaccination against pancreas disease in Atlantic salmon, Salmo salar L., reduces shedding of salmonid alphavirus

• Published in: Veterinary Research
• Main Authors: Skjold, Pål, Sommerset, Ingunn, Frost, Petter, Villoing, Stephane
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2016
• Subjects: [SDV]Life Sciences [q-bio]; Sav’; Atlantic salmon; Salmo salar
• Online Access: https://hal.archives-ouvertes.fr/hal-01480590; https://hal.archives-ouvertes.fr/hal-01480590/document; https://hal.archives-ouvertes.fr/hal-01480590/file/13567_2016_Article_362.pdf; https://doi.org/10.1186/s13567-016-0362-9

International audience AbstractSalmon pancreas disease virus, often referred to as salmonid alphavirus (SAV), causes pancreas disease (PD) in European salmonids. SAV transmits horizontally from fish shedding virus into the water and ocean currents are believed to be a main contributor of viral spread between marine farms. Vaccination against PD is previously shown to reduce mortality and severity of clinical PD. In this study, we demonstrate that vaccination against PD significantly reduces viral shedding from infected individuals. The results suggest that PD vaccination can be an important tool to reduce the infection pressure, a known key risk for PD outbreaks at neighbouring farms.