Platelet function monitoring to adjust antiplatelet therapy in elderly patients stented for an acute coronary syndrome (ANTARCTIC): an open-label, blinded-endpoint, randomised controlled superiority trial.

• Published in: The Lancet
• Main Authors: Cayla, Guillaume, Cuisset, Thomas, Silvain, Johanne, Leclercq, Florence, Manzo-Silberman, Stephane, Saint-Etienne, Christophe, Delarche, Nicolas, Belle, Anne, Range, Grégoire, El Mahmoud, Rami, Carrié, Didier, Belle, Loic, Souteyrand, Geraud, Aubry, Pierre, Sabouret, Pierre, du Fretay, Xavier Halna, Beygui, Farzin, Bonnet, Jean Louis, Lattuca, Benoit, Pouillot, Christophe, Varenne, Olivier, Boueri, Ziad, Van Belle, Eric, Henry, Patrick, Motreff, Pascal, Elhadad, Simon, Salem, Joe-Elie, Abtan, Jérémie, Rousseau, Hélène, Collet, Jean-Philippe, Vicaut, Eric, Montalescot, Gilles
• Other Authors: Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Eli Lilly and Company; Daiichi Sankyo; Stentys; Accriva Diagnostics; Medtronic; Fondation Coeur et Recherche; Assistance Publique des Hopitaux de Paris (Paris, France)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2016
• Subjects: [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system; Antarctic; Stent; Antarc*
• Online Access: https://hal.archives-ouvertes.fr/hal-01478167; https://doi.org/10.1016/S0140-6736(16)31323-X

International audience Elderly patients are at high risk of ischaemic and bleeding events. Platelet function monitoring offers the possibility to individualise antiplatelet therapy to improve the therapeutic risk-benefit ratio. We aimed to assess the effect of platelet function monitoring with treat...