Speeding-up enzyme-catalyzed synthesis of polyamides using omega-amino-alpha-alkoxy-acetate as monomer

• Published in: Polymer
• Main Authors: Poulhès, Florent, Mouysset, Dominique, Gil, Gérard, Bertrand, Michèle P., Gastaldi, Stéphane
• Other Authors: Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2013
• Subjects: [CHIM]Chemical Sciences; Antarc*; Antarctica
• Online Access: https://hal-amu.archives-ouvertes.fr/hal-01460472; https://doi.org/10.1016/j.polymer.2013.05.011

International audience The design of omega-amino-alpha-alkoxy-acetate as monomer enables to dramatically speed up the formation of polyamides catalyzed by the supported lipase B of Candida antarctica. Only 30 min are needed to reach 93% conversion whereas 240 h are necessary to observe the same level of conversion with a monomer devoided of an oxygen atom in position beta relative to the electrophilic carbonyl group. Yields, Mn, Mw, DPn and PDI reach very good values for an enzymatic synthesis of polyamides. (C) 2013 Elsevier Ltd. All rights reserved.