Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases
One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib fam...
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Online Access: | https://hal.archives-ouvertes.fr/hal-01448408 https://doi.org/10.1007/s10126-013-9544-x |
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ftccsdartic:oai:HAL:hal-01448408v1 2023-05-15T18:15:50+02:00 Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases Rodríguez-Ramilo, Silvia T. De La Herrán, Roberto Ruiz-Rejón, Carmelo Hermida, Miguel Fernández, Carlos Pereiro, Patricia Figueras, Antonio Bouza, Carmen Toro, Miguel A. Martínez, Paulino Fernández, Jesús Dept Mejora Genet Anim Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Universidade de Vigo Dept Genet Universidad de Granada (UGR) University of Sandiago de Compostela Instituto de Agroquímica y Tecnología de Alimentos - Institute of Agrochemistry and Food Technology Valencia (IATA-CSIC) Chercheur indépendant Dept Anim Prod Universidad Politécnica de Madrid (UPM) University of Santiago de Compostela 2014 https://hal.archives-ouvertes.fr/hal-01448408 https://doi.org/10.1007/s10126-013-9544-x en eng HAL CCSD Springer Verlag info:eu-repo/semantics/altIdentifier/doi/10.1007/s10126-013-9544-x info:eu-repo/semantics/altIdentifier/pmid/24078233 hal-01448408 https://hal.archives-ouvertes.fr/hal-01448408 PRODINRA: 372764 doi:10.1007/s10126-013-9544-x PUBMED: 24078233 WOS: 000334996700003 ISSN: 1436-2228 EISSN: 1436-2236 Marine Biotechnology https://hal.archives-ouvertes.fr/hal-01448408 Marine Biotechnology, Springer Verlag, 2014, 16 (3), pp.265-276. ⟨10.1007/s10126-013-9544-x⟩ http://www.springerlink.com qtl turbot viral haemorrhagic septicaemia linear regression maximum likelihood [SDV]Life Sciences [q-bio] info:eu-repo/semantics/article Journal articles 2014 ftccsdartic https://doi.org/10.1007/s10126-013-9544-x 2021-07-24T23:49:02Z One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib families with approximately 90 individuals each were genotyped and evaluated by linear regression and maximum likelihood approaches. In addition, a comparison between QTL detected for resistance and survival time to other important bacterial and parasite diseases affecting turbot (furunculosis and scuticociliatosis) was also carried out. Finally, the relationship between QTL affecting resistance/survival time to the virus and growth-related QTL was also evaluated. Several genomic regions controlling resistance and survival time to VHS were detected. Also significant associations between the evaluated traits and genotypes at particular markers were identified, explaining up to 14 % of the phenotypic variance. Several genomic regions controlling general and specific resistance to different diseases in turbot were detected. A preliminary gene mining approach identified candidate genes related to general or specific immunity. This information will be valuable to develop marker-assisted selection programs and to discover candidate genes related to disease resistance to improve turbot production. Article in Journal/Newspaper Scophthalmus maximus Turbot Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Marine Biotechnology 16 3 265 276 |
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Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
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ftccsdartic |
language |
English |
topic |
qtl turbot viral haemorrhagic septicaemia linear regression maximum likelihood [SDV]Life Sciences [q-bio] |
spellingShingle |
qtl turbot viral haemorrhagic septicaemia linear regression maximum likelihood [SDV]Life Sciences [q-bio] Rodríguez-Ramilo, Silvia T. De La Herrán, Roberto Ruiz-Rejón, Carmelo Hermida, Miguel Fernández, Carlos Pereiro, Patricia Figueras, Antonio Bouza, Carmen Toro, Miguel A. Martínez, Paulino Fernández, Jesús Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
topic_facet |
qtl turbot viral haemorrhagic septicaemia linear regression maximum likelihood [SDV]Life Sciences [q-bio] |
description |
One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib families with approximately 90 individuals each were genotyped and evaluated by linear regression and maximum likelihood approaches. In addition, a comparison between QTL detected for resistance and survival time to other important bacterial and parasite diseases affecting turbot (furunculosis and scuticociliatosis) was also carried out. Finally, the relationship between QTL affecting resistance/survival time to the virus and growth-related QTL was also evaluated. Several genomic regions controlling resistance and survival time to VHS were detected. Also significant associations between the evaluated traits and genotypes at particular markers were identified, explaining up to 14 % of the phenotypic variance. Several genomic regions controlling general and specific resistance to different diseases in turbot were detected. A preliminary gene mining approach identified candidate genes related to general or specific immunity. This information will be valuable to develop marker-assisted selection programs and to discover candidate genes related to disease resistance to improve turbot production. |
author2 |
Dept Mejora Genet Anim Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Universidade de Vigo Dept Genet Universidad de Granada (UGR) University of Sandiago de Compostela Instituto de Agroquímica y Tecnología de Alimentos - Institute of Agrochemistry and Food Technology Valencia (IATA-CSIC) Chercheur indépendant Dept Anim Prod Universidad Politécnica de Madrid (UPM) University of Santiago de Compostela |
format |
Article in Journal/Newspaper |
author |
Rodríguez-Ramilo, Silvia T. De La Herrán, Roberto Ruiz-Rejón, Carmelo Hermida, Miguel Fernández, Carlos Pereiro, Patricia Figueras, Antonio Bouza, Carmen Toro, Miguel A. Martínez, Paulino Fernández, Jesús |
author_facet |
Rodríguez-Ramilo, Silvia T. De La Herrán, Roberto Ruiz-Rejón, Carmelo Hermida, Miguel Fernández, Carlos Pereiro, Patricia Figueras, Antonio Bouza, Carmen Toro, Miguel A. Martínez, Paulino Fernández, Jesús |
author_sort |
Rodríguez-Ramilo, Silvia T. |
title |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
title_short |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
title_full |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
title_fullStr |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
title_full_unstemmed |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
title_sort |
identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (vhs) in turbot (scophthalmus maximus ) : a comparison between bacterium, parasite and virus diseases |
publisher |
HAL CCSD |
publishDate |
2014 |
url |
https://hal.archives-ouvertes.fr/hal-01448408 https://doi.org/10.1007/s10126-013-9544-x |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
ISSN: 1436-2228 EISSN: 1436-2236 Marine Biotechnology https://hal.archives-ouvertes.fr/hal-01448408 Marine Biotechnology, Springer Verlag, 2014, 16 (3), pp.265-276. ⟨10.1007/s10126-013-9544-x⟩ http://www.springerlink.com |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1007/s10126-013-9544-x info:eu-repo/semantics/altIdentifier/pmid/24078233 hal-01448408 https://hal.archives-ouvertes.fr/hal-01448408 PRODINRA: 372764 doi:10.1007/s10126-013-9544-x PUBMED: 24078233 WOS: 000334996700003 |
op_doi |
https://doi.org/10.1007/s10126-013-9544-x |
container_title |
Marine Biotechnology |
container_volume |
16 |
container_issue |
3 |
container_start_page |
265 |
op_container_end_page |
276 |
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1766189063239368704 |