Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron
International audience The Pacific oyster Crassostrea gigas is the main oyster species produced in the world, and a key coastal economic resource in France. High mortalities affect Pacific oysters since 2008 in France and Europe. Their origins have been attributed to a combination of biotic and abio...
Published in: | Aquatic Toxicology |
---|---|
Main Authors: | , , , , , , , , |
Other Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2016
|
Subjects: | |
Online Access: | https://hal-sde.archives-ouvertes.fr/hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107/document https://hal-sde.archives-ouvertes.fr/hal-01311107/file/Rondon-2016-AquatToxicol-Transcriptomal-manuscrit.pdf https://doi.org/10.1016/j.aquatox.2016.03.007 |
id |
ftccsdartic:oai:HAL:hal-01311107v1 |
---|---|
record_format |
openpolar |
spelling |
ftccsdartic:oai:HAL:hal-01311107v1 2023-05-15T15:58:25+02:00 Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron Rondon, Rodolfo Akcha, F. Alonso, P. Menard, D. Rouxel, J. Montagnani, Caroline Mitta, Guillaume Cosseau, Céline Grunau, Christoph Interactions Hôtes-Pathogènes-Environnements (IHPE) Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Perpignan Via Domitia (UPVD) Institut Français de Recherche pour l'Exploitation de la Mer - Atlantique (IFREMER Atlantique) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) 2016 https://hal-sde.archives-ouvertes.fr/hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107/document https://hal-sde.archives-ouvertes.fr/hal-01311107/file/Rondon-2016-AquatToxicol-Transcriptomal-manuscrit.pdf https://doi.org/10.1016/j.aquatox.2016.03.007 en eng HAL CCSD Elsevier info:eu-repo/semantics/altIdentifier/doi/10.1016/j.aquatox.2016.03.007 hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107/document https://hal-sde.archives-ouvertes.fr/hal-01311107/file/Rondon-2016-AquatToxicol-Transcriptomal-manuscrit.pdf doi:10.1016/j.aquatox.2016.03.007 info:eu-repo/semantics/OpenAccess ISSN: 0166-445X Aquatic Toxicology https://hal-sde.archives-ouvertes.fr/hal-01311107 Aquatic Toxicology, Elsevier, 2016, 175, pp.47-55. ⟨10.1016/j.aquatox.2016.03.007⟩ Mollusk Oyster diuron transcriptomic ecotoxicology [SDE]Environmental Sciences info:eu-repo/semantics/article Journal articles 2016 ftccsdartic https://doi.org/10.1016/j.aquatox.2016.03.007 2021-11-07T02:05:06Z International audience The Pacific oyster Crassostrea gigas is the main oyster species produced in the world, and a key coastal economic resource in France. High mortalities affect Pacific oysters since 2008 in France and Europe. Their origins have been attributed to a combination of biotic and abiotic factors, underlining the importance of environment quality. The impact of water pollution has been pointed out and one of the pollutants, the genotoxic herbicide diuron, occurs at high concentrations all along the French coasts. Previous work has revealed that a parental exposure to diuron had a strong impact on hatching rates and offspring development even if spats were not exposed to diuron themselves. In this study, we explored for the first time the transcriptional changes occurring in oyster spats (non exposed) originating from genitors exposed to an environmentally relevant concentration of diuron during gametogenesis using the RNAseq methodology. We identified a transcriptomic remodeling revealing an effect of the herbicide. Different molecular pathways involved in energy production, translation and cell proliferation are particularly disturbed. This analysis revealed modulated candidate genes putatively involved in response to oxidative stress and mitochondrial damage in offspring of genitors exposed to diuron. Complementary measures of the activity of enzymes involved in these latter processes corroborate the results obtained at the transcriptomic level. In addition, our results suggested an increase in energy production and mitotic activity in 5-month-spats from diuron-exposed genitors. These results could correspond to a “catch-up growth” phenomenon allowing the spats from diuron-exposed genitors, which displayed a growth delay at 3 months, to gain a normal size when they reach the age of 6 months. These results indicate that exposure to a concentration of diuron that is frequently encountered in the field during the oyster’s gametogenesis stage can impact the next generation and may result in fitness ... Article in Journal/Newspaper Crassostrea gigas Pacific oyster Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Pacific Aquatic Toxicology 175 47 55 |
institution |
Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
Mollusk Oyster diuron transcriptomic ecotoxicology [SDE]Environmental Sciences |
spellingShingle |
Mollusk Oyster diuron transcriptomic ecotoxicology [SDE]Environmental Sciences Rondon, Rodolfo Akcha, F. Alonso, P. Menard, D. Rouxel, J. Montagnani, Caroline Mitta, Guillaume Cosseau, Céline Grunau, Christoph Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
topic_facet |
Mollusk Oyster diuron transcriptomic ecotoxicology [SDE]Environmental Sciences |
description |
International audience The Pacific oyster Crassostrea gigas is the main oyster species produced in the world, and a key coastal economic resource in France. High mortalities affect Pacific oysters since 2008 in France and Europe. Their origins have been attributed to a combination of biotic and abiotic factors, underlining the importance of environment quality. The impact of water pollution has been pointed out and one of the pollutants, the genotoxic herbicide diuron, occurs at high concentrations all along the French coasts. Previous work has revealed that a parental exposure to diuron had a strong impact on hatching rates and offspring development even if spats were not exposed to diuron themselves. In this study, we explored for the first time the transcriptional changes occurring in oyster spats (non exposed) originating from genitors exposed to an environmentally relevant concentration of diuron during gametogenesis using the RNAseq methodology. We identified a transcriptomic remodeling revealing an effect of the herbicide. Different molecular pathways involved in energy production, translation and cell proliferation are particularly disturbed. This analysis revealed modulated candidate genes putatively involved in response to oxidative stress and mitochondrial damage in offspring of genitors exposed to diuron. Complementary measures of the activity of enzymes involved in these latter processes corroborate the results obtained at the transcriptomic level. In addition, our results suggested an increase in energy production and mitotic activity in 5-month-spats from diuron-exposed genitors. These results could correspond to a “catch-up growth” phenomenon allowing the spats from diuron-exposed genitors, which displayed a growth delay at 3 months, to gain a normal size when they reach the age of 6 months. These results indicate that exposure to a concentration of diuron that is frequently encountered in the field during the oyster’s gametogenesis stage can impact the next generation and may result in fitness ... |
author2 |
Interactions Hôtes-Pathogènes-Environnements (IHPE) Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Perpignan Via Domitia (UPVD) Institut Français de Recherche pour l'Exploitation de la Mer - Atlantique (IFREMER Atlantique) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) |
format |
Article in Journal/Newspaper |
author |
Rondon, Rodolfo Akcha, F. Alonso, P. Menard, D. Rouxel, J. Montagnani, Caroline Mitta, Guillaume Cosseau, Céline Grunau, Christoph |
author_facet |
Rondon, Rodolfo Akcha, F. Alonso, P. Menard, D. Rouxel, J. Montagnani, Caroline Mitta, Guillaume Cosseau, Céline Grunau, Christoph |
author_sort |
Rondon, Rodolfo |
title |
Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
title_short |
Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
title_full |
Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
title_fullStr |
Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
title_full_unstemmed |
Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
title_sort |
transcriptional changes in crassostrea gigas oyster spat following a parental exposure to the herbicide diuron |
publisher |
HAL CCSD |
publishDate |
2016 |
url |
https://hal-sde.archives-ouvertes.fr/hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107/document https://hal-sde.archives-ouvertes.fr/hal-01311107/file/Rondon-2016-AquatToxicol-Transcriptomal-manuscrit.pdf https://doi.org/10.1016/j.aquatox.2016.03.007 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
ISSN: 0166-445X Aquatic Toxicology https://hal-sde.archives-ouvertes.fr/hal-01311107 Aquatic Toxicology, Elsevier, 2016, 175, pp.47-55. ⟨10.1016/j.aquatox.2016.03.007⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.aquatox.2016.03.007 hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107 https://hal-sde.archives-ouvertes.fr/hal-01311107/document https://hal-sde.archives-ouvertes.fr/hal-01311107/file/Rondon-2016-AquatToxicol-Transcriptomal-manuscrit.pdf doi:10.1016/j.aquatox.2016.03.007 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1016/j.aquatox.2016.03.007 |
container_title |
Aquatic Toxicology |
container_volume |
175 |
container_start_page |
47 |
op_container_end_page |
55 |
_version_ |
1766394156545998848 |