Fatty acids linked to cardiovascular mortality are associated with risk factors

• Main Authors: Ebbesson, Sven O. E., Voruganti, Venkata S., Higgins, Paul B., Fabsitz, Richard R., Ebbesson, Lars O., Laston, Sandra, Harris, William S., Kennish, John, Umans, Benjamin D., Wang, Hong, Devereux, Richard B., Okin, Peter M., Weissman, Neil J., MacCluer, Jean W., Umans, Jason G., Howard, Barbara V.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2015
• Subjects: Triglycerides; Cardiovascular Diseases; Fasting; Mortality; Risk; Regression Analysis; Body Mass Index; Myristic Acids; Blood; Blood Pressure; Cross-Sectional Studies; Glucose; C-Reactive Protein; Lipoproteins; HDL; Cholesterol; LDL; Cell Membrane; Fatty Acids; Stroke; Linoleic Acids; Heart Rate; Palmitates; Risk Factors; Carbohydrates; Insulin; Plasma; Diet; Circumpolar Health; International Journal of Circumpolar Health
• Online Access: https://doi.org/10.17615/1ecq-8565; https://cdr.lib.unc.edu/downloads/wp988s50n?file=thumbnail; https://cdr.lib.unc.edu/downloads/wp988s50n

Although saturated fatty acids (FAs) have been linked to cardiovascular mortality, it is not clear whether this outcome is attributable solely to their effects on low-density lipoprotein cholesterol (LDL-C) or whether other risk factors are also associated with FAs. The Western Alaskan Native population, with its rapidly changing lifestyles, shift in diet from unsaturated to saturated fatty acids and dramatic increase in cardiovascular disease (CVD), presents an opportunity to elucidate any associations between specific FAs and known CVD risk factors.